Patient Knowledge, Beliefs and Barriers to Hepatitis D Care

NCT06017375 | Unknown DMC

• 1 other identifier: 330645
• Study Type: observational
• Target: 113
• Locations: 0 countries
• Sites: N/A

Brief Summary

A project to understand the determinants of health behaviour among those with chronic hepatitis D virus (HDV) infection, under the care of the viral hepatitis service at Kings College Hospital (KCH). This is to improve and implement pathways and patient information distribution to improve access to care in an ethnically diverse population living with HDV in the UK. Kings college hospital NHS Foundation Trust is uniquely placed and serves a large diverse population from areas such as pan pacific Asia, Eastern Europe and regions in Africa, where English is not their first language. This diversity is also seen in other London Hospitals but less so in other parts of the UK.

Conditions

Hepatitis, Delta

Outcome Measures

Primary Outcomes (2)

• The overall patient understanding of Hepatitis D Virus diagnosis

  Use of modified CLDQ - HBV survey. Scale of 1-7 with lower scores indicating worse outcomes

  6 months

• Describe overall patient knowledge around HDV

  Modified HBV knowledge scale survey. Yes or No as options

  6 months

Secondary Outcomes (2)

• Describe stigma attached towards HDV

  6 months

• Understand satisfaction with communication regarding HDV care at KCH

  6 months

Interventions

Questionnaire based intervention OTHER

Three validated questionnaires amended from hepatitis B to D (Chronic liver disease questionnaire, self-stigma scale and HBV virus knowledge scale) will be used.

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

Patients with past or current hepatitis D virus infection

You may qualify if:

• Participants 18 years or older.
• HDV infection as diagnosed by high levels of anti-HDV immunoglobulin G (IgG) and immunoglobulin M (IgM), and confirmed by detection of HDV RNA in serum.
• Treated HDV infection
• Willing and able to provide written informed consent.

You may not qualify if:

• Clinically significant medical or psychiatric illness in the past, present, or being evaluated, that may interfere with participant treatment, safety and assessment.

Sponsors & Collaborators

• King's College Hospital NHS Trust: lead

MeSH Terms

Conditions

Hepatitis D

Condition Hierarchy (Ancestors)

Hepatitis, Viral, Human; Virus Diseases; Infections; RNA Virus Infections; Hepatitis; Liver Diseases; Digestive System Diseases

Central Study Contacts

Sital Shah

CONTACT

02032999000; sitalshah@nhs.net

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: August 17, 2023
• First Posted: August 30, 2023
• Study Start: September 1, 2023
• Primary Completion: February 28, 2024
• Study Completion: August 30, 2024
• Last Updated: August 30, 2023

Record last verified: 2023-08

Data Sharing

• IPD Sharing: Will not share