Acute Effect of Resistance Exercise, Neuromuscular Electrical Stimulation, and Transcutaneous Electrical Stimulation Applications on Muscle Activation

NCT06016660 | Completed

• 1 other identifier: EMGHealthy
• Study Type: interventional
• Target: 21
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of our study is to investigate the effects of single-session resistance exercise, neuromuscular electrical stimulation, and transcutaneous electrical stimulation on the level of muscle activation and their superiority over each other on both the ipsilateral and contralateral sides. Our randomized controlled crossover study included 21 participants (13 female, 8 male, age; 27.7±4). Transcutaneous electrical stimulation was used for sensory input. A single-session application was performed only to the right extremities of all participants, and the acute effects on muscle activation on both the ipsilateral and contralateral sides were evaluated. Muscle activation was evaluated with superficial EMG. SPSS® Statistics V22.0 software was used for statistical analysis. As a result of the statistical analysis, a significant increase in activation was found only in the sensory input application group on the ipsilateral side flexor carpi radialis (FCR) (p=0.001), flexor carpi ulnaris (FCU) (p\<0.001), flexor digitorum superficialis (FDS) (p=0.023) and flexor digitorum profundus (FDP) (p=0.003) muscles. On the contralateral side, there was an increase in activation in all muscles (FCR; p\<0.001, FCU; p=0.033, FDS; p=0.017 and FDP; p=0.001) in the resistant exercise group. In addition, there was a significant increase in the activation of certain muscles on the contralateral side in the NMES application group (FCR (p=0.049) and FDP (p=0.016) muscles) and the sensory input application group (FDP (p=0.004) and FDS (p=0.043) muscles). In situations where movement is contraindicated, ipsilateral sensory input can increase the level of muscle activation through both cortical and peripheral neural mechanisms.In addition, resistance exercise to be performed on the contralateral side can be an effective application to increase muscle activation on the ipsilateral side.

Conditions

Motor Activity

Outcome Measures

Primary Outcomes (1)

• Superficial electromyography

  Muscle activation measurement

  through study completion, an average of 1 year

Study Arms (4)

Resistance exercise

EXPERIMENTAL

Resistance exercise

Other: Physiotherapy

Neuromuscular electrical stimulation

EXPERIMENTAL

Neuromuscular electrical stimulation

Other: Physiotherapy

Transcutaneous electrical stimulation

EXPERIMENTAL

Transcutaneous electrical stimulation

Other: Physiotherapy

Control

NO INTERVENTION

No intervention

Interventions

Physiotherapy OTHER

Resistance exercise, Neuromuscular electrical stimulation, and Transcutaneous electrical stimulation

Neuromuscular electrical stimulation; Resistance exercise; Transcutaneous electrical stimulation

Eligibility Criteria

• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• After providing detailed information about the study, individuals who had agreed to participate in the research were included in the study.

You may not qualify if:

• Individuals with any central or peripheral nervous system disease/injury affecting the upper extremity,
• Individuals with a history of orthopedic injury that could impact the study,
• Individuals with a history of neuromuscular disease, congenital anomalies, skin infections, or cognitive impairments,
• Individuals with a history of systemic or metabolic diseases that could potentially affect the study,
• Individuals with a body mass index (BMI) above 30 kg/m2.

Sponsors & Collaborators

• Gazi University: lead

Study Sites (1)

Barış SEVEN

Izmir, Çiğli, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Motor Activity

Interventions

Physical Therapy Modalities

Condition Hierarchy (Ancestors)

Behavior

Intervention Hierarchy (Ancestors)

Therapeutics; Rehabilitation

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: NONE
• Purpose: TREATMENT
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Ph.D. research assistant

Study Record Dates

• First Submitted: June 7, 2023
• First Posted: August 30, 2023
• Study Start: May 1, 2022
• Primary Completion: October 1, 2022
• Study Completion: January 1, 2023
• Last Updated: August 30, 2023

Record last verified: 2023-08

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)