Trajectories of Fatigue and Quality of Life in People With Both Operable Pancreatic Tumor and Diabetes Mellitus

NCT06013228 | Completed

• 1 other identifier: 202302123RIND
• Study Type: observational
• Target: 99
• Locations: 1 country
• Sites: 1

Brief Summary

In people with both burdens of OPT and DM, fatigue is the most common and deliberating symptom that likely impacts their quality of life and diabetes self-management. However, little is known about the longitudinal relationships among fatigue, its influencing factors, glycemic status, diabetes self-management, and quality of life in people with both OPT and DM during the first-year post-operation. Thus, the purposes of this study are to (1) describe the trajectories of fatigue, HbA1c, diabetes self-management, and quality of life in people with OPT and DM within 12 months post-operation; (2) examine the relationships among the trajectories of fatigue, its influencing factors, diabetes self-management, and quality of life in people with OPT and DM; and (3) understand the experiences of people with both OPT and DM regarding changes in challenges with diabetes, fatigue, diabetes self-management, diabetes care needs, and quality of life.

Conditions

Operable Pancreatic Tumor; Diabetes Mellitus

Outcome Measures

Primary Outcomes (1)

• Fatigue

  Fatigue Symptom Inventory

  baseline, 3, 6, 9, and 12 months post baseline

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

The participants will be recruited from a pancreatic surgical outpatient department (OPD) at a medical center located in northern Taiwan.

You may qualify if:

• Operable pancreatic tumor within 5 years and are following up at the outpatient department
• Diagnosed with diabetes mellitus
• Aged 18 or above
• Can communicate in Mandarin or Taiwanese
• Agree to participate and sign the informed consent form

You may not qualify if:

• Under active treatment for cancer other than pancreatic tumor
• Have a cognitive impairment
• Do not know that they have pancreatic tumor
• Diagnosed with chronic fatigue syndrome or fibromyalgia

Sponsors & Collaborators

• National Taiwan University Hospital: lead

Study Sites (1)

National Taiwan University Hospital

Taipei, Taiwan

Location

MeSH Terms

Conditions

Diabetes Mellitus

Condition Hierarchy (Ancestors)

Glucose Metabolism Disorders; Metabolic Diseases; Nutritional and Metabolic Diseases; Endocrine System Diseases

Study Officials

• Hsuan-Ju Kuo, PhD

  National Taiwan University

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: August 22, 2023
• First Posted: August 28, 2023
• Study Start: August 30, 2023
• Primary Completion: March 27, 2026
• Study Completion: March 27, 2026
• Last Updated: April 29, 2026

Record last verified: 2026-04

Data Sharing

• IPD Sharing: Will not share

Locations

TW (1)