NCT06010433

Brief Summary

This is an Observational Device Registry Study of CERAMENT\|G in normal use in accordance with the IFU. It will run for a period of three years from enrolment of the first patient into the Study at each Site, before being subject to review. A Device Registry is a form of observational study that concerns the performance of a device in normal use. It is intended to collect data that is reflective of 'real world' device performance.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
100

participants targeted

Target at P50-P75 for all trials

Timeline
29mo left

Started Aug 2023

Longer than P75 for all trials

Geographic Reach
1 country

3 active sites

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress53%
Aug 2023Sep 2028

First Submitted

Initial submission to the registry

May 25, 2023

Completed
3 months until next milestone

Study Start

First participant enrolled

August 17, 2023

Completed
7 days until next milestone

First Posted

Study publicly available on registry

August 24, 2023

Completed
5.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

September 22, 2028

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

September 22, 2028

Last Updated

September 26, 2025

Status Verified

September 1, 2025

Enrollment Period

5.1 years

First QC Date

May 25, 2023

Last Update Submit

September 23, 2025

Conditions

Outcome Measures

Primary Outcomes (1)

  • Primary Outcomes

    • Device safety - any unexpected device performance, complaints, adverse events, adverse device effects, SAEs throughout study period.

    12 months

Secondary Outcomes (3)

  • Secondary Outcome

    12 months

  • Secondary Outcome

    6 and 12 months

  • Secondary Outcome

    12 months

Interventions

* Primary mode of action is to be a resorbable ceramic bone graft substitute intended to fill gaps and voids in the skeleton system to promote bone healing. CERAMENT ™\|G provides a void/gap filler that during the surgical procedure can augment hardware and bone alignments. * Secondary mode of action is to prevent colonization of Gentamicin sensitive microorganisms in order to protect bone healing.

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

The racial, gender and ethnic characteristics of the individuals approached for participation in this Observational Registry Study shall reflect the demographics of patients that would ordinarily receive CERAMENT\|G for the treatment of their condition at the designated investigative centres. No individuals shall be excluded from participation in the Observational Registry Study based on race, nationality, ethnicity, gender, or sexuality

You may qualify if:

  • years and over (on the day of surgery)
  • receive CERAMENT\|G as a component of their treatment at a participating, contracted centre or healthcare provider, in accordance with the IFU for the implanted product
  • In receipt of patient information leaflet and have signed appropriately designed informed consent form.

You may not qualify if:

  • Any off-label use

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (3)

North Park Podiatry

San Diego, California, 92104, United States

RECRUITING

OrthoCarolina

Charlotte, North Carolina, 28207, United States

RECRUITING

University Hospitals Cleveland Medical Center

Cleveland, Ohio, 44106, United States

RECRUITING

Central Study Contacts

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
PROSPECTIVE
Target Duration
12 Months
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 25, 2023

First Posted

August 24, 2023

Study Start

August 17, 2023

Primary Completion (Estimated)

September 22, 2028

Study Completion (Estimated)

September 22, 2028

Last Updated

September 26, 2025

Record last verified: 2025-09

Data Sharing

IPD Sharing
Will not share

Locations