Control of Edema in the Knee in Patients With Knee Osteoarthritis

NCT06010394 | Completed

• 1 other identifier: Uskudar50
• Study Type: interventional
• Target: 75
• Locations: 1 country
• Sites: 1

Brief Summary

The aim of this study was to compare the effectiveness of exercise and classical massage in the control of knee edema in patients with knee osteoarthritis.

Conditions

Knee Osteoarthritis; Edema; Edema Leg

Keywords

massage

Outcome Measures

Primary Outcomes (2)

• Knee Injury and Osteoarthritis Outcome Score

  It is used to detect symptoms and restrictions in current work that individuals do in daily life. The test is collected under 2 main headings, consisting of 6 questions about the effect of symptoms and 8 sub-activities that question the status of the activity. The answer to each question in the test is scored between 0-5. The scores that the person gets from each question are added together and these scores are divided by 70 and multiplied by 100. High score means low quality of life.

  4 weeks

• Western Ontario and McMaster Universities Osteoarthritis Index

  Pain, joint stiffness and functional status; Evaluated with the Arthritis Index of Western Ontario and McMaster Universities. The scale is a disease-specific, multidimensional, self-administered health status tool used in hip or knee osteoarthritis27. It consists of 24 questions on pain, stiffness and physical disability and is approximately 10 min. can be completed in Western Ontario and McMaster Universities Osteoarthritis Index consists of 24 questions under three sub-headings. Pain consists of 5 questions, stiffness 2 questions and function 17 questions. Each sub-parameter is scored between 0-4 points. Accordingly, it is classified as pain (0-20), stiffness (0-8) and function (0-68). A high score indicates poor health, a low score indicates good health.

  4 weeks

Study Arms (3)

control group

ACTIVE COMPARATOR

commensal physiotherapy will be applied

Other: conventional physiotherapy

exercise group

EXPERIMENTAL

exercises will be given

Other: conventional physiotherapy; Other: exercises for the knee area

massage group

EXPERIMENTAL

massage will be done

Other: conventional physiotherapy; Other: payment oriented massage

Interventions

conventional physiotherapy OTHER

ultrasound electrotherapy cold applications

control group; exercise group; massage group

exercises for the knee area OTHER

range of motion exercises strengthening exercises exercises to reduce edema

exercise group

payment oriented massage OTHER

10 / 15-minute massage treatments to reduce payment

massage group

Eligibility Criteria

• Age: 30 Years - 65 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Being between the ages of 30-65
• Patients with a diagnosis of osteoarthritis in stage 2 and stage 3 according to Kellgren-Lawrence criteria(1) and also with measurable edema

You may not qualify if:

• Inability to continue treatment regularly
• situations that prevent you from doing the exercise
• inflammation that interferes with massage.

Sponsors & Collaborators

• Uskudar University: lead

Study Sites (1)

Uskudar university

Istanbul, Turkey (Türkiye)

Location

Related Publications (4)

• Maricar N, Callaghan MJ, Parkes MJ, Felson DT, O'Neill TW. Clinical assessment of effusion in knee osteoarthritis-A systematic review. Semin Arthritis Rheum. 2016 Apr;45(5):556-63. doi: 10.1016/j.semarthrit.2015.10.004. Epub 2015 Oct 22.

  PMID: 26581486 BACKGROUND

• Hofmann S, Kramer J, Vakil-Adli A, Aigner N, Breitenseher M. Painful bone marrow edema of the knee: differential diagnosis and therapeutic concepts. Orthop Clin North Am. 2004 Jul;35(3):321-33, ix. doi: 10.1016/j.ocl.2004.04.005.

  PMID: 15271540 BACKGROUND

• Molfetta L, Florian A, Saviola G, Frediani B. Bone Marrow Edema: pathogenetic features. Clin Ter. 2022 Sep-Oct;173(5):434-439. doi: 10.7417/CT.2022.2459.

  PMID: 36155729 BACKGROUND

• Kan HS, Chan PK, Chiu KY, Yan CH, Yeung SS, Ng YL, Shiu KW, Ho T. Non-surgical treatment of knee osteoarthritis. Hong Kong Med J. 2019 Apr;25(2):127-133. doi: 10.12809/hkmj187600. Epub 2019 Mar 28.

  PMID: 30919810 BACKGROUND

MeSH Terms

Conditions

Osteoarthritis, Knee; Edema

Interventions

Exercise

Condition Hierarchy (Ancestors)

Osteoarthritis; Arthritis; Joint Diseases; Musculoskeletal Diseases; Rheumatic Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Motor Activity; Movement; Musculoskeletal Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Officials

• Enver Deniz YILDIRIM

  Uskudar University

  STUDY CHAIR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: SINGLE
• Who Masked: OUTCOMES ASSESSOR
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Asst. Prof. Dr.

Model Details: classical physical therapy, exercise therapy, classical massage

Study Record Dates

• First Submitted: August 18, 2023
• First Posted: August 24, 2023
• Study Start: September 1, 2023
• Primary Completion: October 15, 2023
• Study Completion: December 6, 2023
• Last Updated: December 7, 2023

Record last verified: 2023-12

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)