NCT06008847

Brief Summary

The CESCAIL study tests the use of Artificial Intelligence (AI) on a video taken from a minimally-invasive imaging device, to improve efficiency and accuracy of the detection of polyps, which are little outgrowths within the lining of the bowel.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
720

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Feb 2022

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

February 9, 2022

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

April 7, 2022

Completed
1.4 years until next milestone

First Posted

Study publicly available on registry

August 24, 2023

Completed
1.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 16, 2024

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

October 16, 2024

Completed
Last Updated

March 9, 2026

Status Verified

February 1, 2026

Enrollment Period

2.7 years

First QC Date

April 7, 2022

Last Update Submit

March 6, 2026

Conditions

Bowel Cancer

Keywords

bowelcancerAI

Outcome Measures

Primary Outcomes (2)

  • Sensitivity and specificity of polyp detection in AI enabled CCE reporting

    Sensitivity and specificity of polyp detection in AI enabled CCE reporting

    11 months

  • Time taken to read video by clinicians and AI tool

    Time taken to read video by clinicians and AI tool

    11 months

Study Arms (1)

Lower Gastrointestinal Symptoms

Participant aged over 18 with referred lower gastrointestinal symptoms

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Male or female, aged 18 and over

You may qualify if:

  • Aged 18 or over
  • Patients who have been selected by overseeing clinician meeting NHS England criteria to undergo colon capsule endoscopy as part of their standard of care

You may not qualify if:

  • Patients unable to provide consent to take part in the study

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

University Hospitals Coventry and Warwickshire

Coventry, Coventry, CV2 2DX, United Kingdom

Location

MeSH Terms

Conditions

Intestinal NeoplasmsNeoplasms

Condition Hierarchy (Ancestors)

Gastrointestinal NeoplasmsDigestive System NeoplasmsNeoplasms by SiteDigestive System DiseasesGastrointestinal DiseasesIntestinal Diseases

Study Design

Study Type
observational
Observational Model
OTHER
Time Perspective
PROSPECTIVE
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 7, 2022

First Posted

August 24, 2023

Study Start

February 9, 2022

Primary Completion

October 16, 2024

Study Completion

October 16, 2024

Last Updated

March 9, 2026

Record last verified: 2026-02

Data Sharing

IPD Sharing
Will not share

Locations

GB(1)