Pain Related Variables

NCT06007443 | Completed

• 1 other identifier: CPM-TS-2PD
• Study Type: interventional
• Target: 46
• Locations: 1 country
• Sites: 1

Brief Summary

Chronic neck pain is a common problem among the general population. Patients with chronic neck pain used health care services twice as much as the population on average, mainly due to intense pain intensity. It is well-known that pain intensity depends on the association of pain processing in several levels of central pain processing. Identifying the association between conditioned pain modulation, temporal summation, and somatosensory representation, all represent separate central pain processing, will provide an opportunity to develop treatment strategies.

Conditions

Chronic Neck Pain; Musculoskeletal Pain; Pain Modulation; Cortical Plasticity; Conditioned Pain Modulation; Temporal Summation

Outcome Measures

Primary Outcomes (1)

• pressure pain threshold

  The pressure pain threshold (PPTs) of the upper trapezius and dominant tibialis anterior muscles will be evaluated. For the upper trapezius muscle, assessment will be made approximately 5 to 8 cm superomedial to the superior angle of the scapula. For the tibialis anterior muscle, the assessment will be made muscle belly, which is approximately 2.5 cm lateral and 5 cm inferior to the tibial tubercle. Palpation during resisted active dorsiflexion ensured that the tibialis anterior muscle belly had been found. Pressure pain thresholds will assessed using a pressure algometer (Algometer) with a stimulation area of 1 cm2. The increment rate of pressure will be kept at approximately 1 kg/cm2/s. The first time the pressure perceived as pain will be recorded as a PPTs. Two PPT assessments with a 30 second will be completed, and the average was used for statistical analysis.

  'baseline'

Secondary Outcomes (3)

• temporal summation

  'baseline'

• conditioned pain modulation

  'baseline'

• tactile acuity

  'baseline'

Study Arms (1)

patients with neck pain

EXPERIMENTAL

conditioned pain modulation, temporal summation and two-point discrimination will be evaluated in all included participants. Average pain intensity will be asked

Other: pain related variables assessment

Interventions

pain related variables assessment OTHER

Pressure pain threshold, conditioned pain modulation, temporal summation, and two-point discrimination will be evaluated on the upper trapezius muscle. Average pain intensity will be asked.

patients with neck pain

Eligibility Criteria

• Age: 20 Years - 60 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• pain in the back of the neck region
• pain longer than 3 months
• pain intensity at least 3 based on the visual analog scale

You may not qualify if:

• vertebra fracture
• fibromyalgia
• chronic fatigue syndrome
• surgery to the neck or shoulder
• radicular pain
• neurologic deficit due to disk hernia
• spinal stenosis

Sponsors & Collaborators

• Hacettepe University: lead

Study Sites (1)

Hacettepe University

Ankara, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Musculoskeletal Pain

Condition Hierarchy (Ancestors)

Muscular Diseases; Musculoskeletal Diseases; Pain; Neurologic Manifestations; Signs and Symptoms; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: SCREENING
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal investigator

Study Record Dates

• First Submitted: July 4, 2023
• First Posted: August 23, 2023
• Study Start: January 28, 2023
• Primary Completion: September 28, 2023
• Study Completion: November 25, 2023
• Last Updated: November 29, 2023

Record last verified: 2023-08

Locations

TU (1)