A Clinical Model for Dialysis Discontinuation in AKI
A Clinical Model to Predict Successful Renal Replacement Therapy (RRT) Discontinuation in Patients With Acute Kidney Injury (AKI)
1 other identifier
observational
124
1 country
1
Brief Summary
A retrospective study evaluating AKI patients in whom RRT was interrupted for at least 48 hours. Patients who were still RRT-independent 7 days after initial RRT cessation were included in the "Success" group, as opposed to the "Failure" group. Baseline characteristics and variables at the time of RRT interruption were collected. Multivariable analysis was performed and a model was generated to evaluate the prediction of success.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Oct 2020
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
October 1, 2020
CompletedPrimary Completion
Last participant's last visit for primary outcome
February 1, 2022
CompletedStudy Completion
Last participant's last visit for all outcomes
February 1, 2022
CompletedFirst Submitted
Initial submission to the registry
August 16, 2023
CompletedFirst Posted
Study publicly available on registry
August 23, 2023
CompletedAugust 23, 2023
August 1, 2023
1.3 years
August 16, 2023
August 16, 2023
Conditions
Outcome Measures
Primary Outcomes (1)
Success in RRT discontinuation
To be alive and free from RRT 7 days after interrupting RRT.
7 days
Study Arms (2)
Success
Patients who were alive and free from RRT 7 days after interrupting RRT.
Failure
Patients who were not alive or who needed to dialyse again after interrupting RRT for at least 48h.
Eligibility Criteria
Critically ill patients from a large tertiary care hospital receiving kidney replacement therapy due to AKI.
You may not qualify if:
- Patients who had kidney replacement therapy interrupted exclusively due to haemodynamic instability, death or decision for palliative care were excluded.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
University of São Paulo School of Medicine
São Paulo, São Paulo, 01246903, Brazil
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- RETROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
August 16, 2023
First Posted
August 23, 2023
Study Start
October 1, 2020
Primary Completion
February 1, 2022
Study Completion
February 1, 2022
Last Updated
August 23, 2023
Record last verified: 2023-08