NCT06004583

Brief Summary

Objective: Acne vulgaris, an inflammatory disease, was investigated in this study with the claim that C-reactive protein (CRP) / albumin ratio and some hematological parameter ratios have the potential to be used as inflammatory markers to monitor disease severity and prognosis. Methods: A descriptive cross-sectional study was conducted with two groups of patients aged 18-65 years, 61 patients diagnosed with acne vulgaris and 35 healthy control patients, and routine hemogram and biochemical parameters were compared. The Global Acne Severity Index was used to determine the severity of acne vulgaris.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
96

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Jan 2022

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 5, 2022

Completed
1.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

February 2, 2023

Completed
3 months until next milestone

Study Completion

Last participant's last visit for all outcomes

May 1, 2023

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

August 16, 2023

Completed
6 days until next milestone

First Posted

Study publicly available on registry

August 22, 2023

Completed
Last Updated

August 22, 2023

Status Verified

August 1, 2023

Enrollment Period

1.1 years

First QC Date

August 16, 2023

Last Update Submit

August 21, 2023

Conditions

Acne Vulgaris

Keywords

acne vulgarisCRP albumin ratio

Outcome Measures

Primary Outcomes (1)

  • CRP/albumin ratio

    Statistical difference between groups

    3 months

Secondary Outcomes (1)

  • Usage of CRP/albumin ratio as a Biomarker

    3 months

Study Arms (2)

Acne group

Acne Vulgaris Diagnosed Patients

Diagnostic Test: Biochemical blood analysis

Control group

Healthy participants

Diagnostic Test: Biochemical blood analysis

Interventions

Biochemical blood analysisDIAGNOSTIC_TEST

Serum CRP and albumin levels

Acne groupControl group

Eligibility Criteria

Age18 Years - 40 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)
Sampling MethodProbability Sample
Study Population

Acne vulgaris patients and control healthy individuals

You may qualify if:

  • Acne vulgaris patients diagnosed by a dermatologist
  • Healthy participants without acne
  • years of age
  • Voluntary participation

You may not qualify if:

  • Aged below18 or above 40 years
  • Not voluntarily participated patents
  • Pregnants, breast milked mothers, emergency situations

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

AtaturkU

Erzurum, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Acne Vulgaris

Condition Hierarchy (Ancestors)

Acneiform EruptionsSkin DiseasesSkin and Connective Tissue DiseasesSebaceous Gland Diseases

Study Design

Study Type
observational
Observational Model
CASE CONTROL
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Ass.Prof

Study Record Dates

First Submitted

August 16, 2023

First Posted

August 22, 2023

Study Start

January 5, 2022

Primary Completion

February 2, 2023

Study Completion

May 1, 2023

Last Updated

August 22, 2023

Record last verified: 2023-08

Locations

TU(1)