Our Anesthesia Experiences in Hepatopancreatobiliary Surgery Practices: a Retrospective Study

NCT06002776 | Unknown

• 1 other identifier: Sisli Hamidiye Etfal TRH
• Study Type: observational
• Target: 6
• Locations: 1 country
• Sites: 1

Brief Summary

Has the evolving anesthetic management in major abdominal surgeries had a positive impact on patients' one-year postoperative mortality and length of hospital stay? Which of the anesthetic management parameters have influenced mortality and hospital stay duration in these patients? To address these questions, we have planned to retrospectively review patients who underwent surgery at our center.

Conditions

Experience, Life

Keywords

major abdominal surgery; Revised Cardiac Risk Index; Epidural analgesia; perioperative fluid management; ERAS protocols

Outcome Measures

Primary Outcomes (1)

• form a comprehensive understanding of our anesthesia experiences during the preoperative, perioperative, and postoperative periods in this patient group

  october2017-february2022

Secondary Outcomes (1)

• assess the influence of preoperative and perioperative anesthetic management on the morbidity and mortality of these patients.

  october2017-february2022

Study Arms (1)

preoperative and perioperative anaesthetic management

We have planned to retrospectively review data for patients aged 18 and above who underwent major abdominal surgery at our center between October 2017 and February 2022. The study aims to record data regarding the administration of thromboprophylaxis, preoperative hemoglobin values, and Revised Cardiac Risk Index scores and their impact on one-year postoperative mortality. Additionally, we intend to examine the effects of the amount of fluid administered during the perioperative period, the application of epidural analgesia, and the use of blood products on hospital stay duration and one-year postoperative mortality.

Other: a retrospective study

Interventions

a retrospective study OTHER

a retrospective study

preoperative and perioperative anaesthetic management

Eligibility Criteria

• Age: 18 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

data from all patients aged 18 and above who underwent major abdominal surgery with diagnoses of liver malignancy, cholangiocarcinoma, and pancreatic malignancy

You may qualify if:

• The study will include data from patients who have undergone their first operation with the diagnoses of liver malignancy, cholangiocarcinoma, and pancreatic malignancy during the period from October 2017 to February 2022.

You may not qualify if:

• Data from patients who were deemed inoperable during the perioperative period after being taken into surgery with their current diagnosis, as well as data from patients who underwent repeat operations, were excluded from the study for their second and subsequent hospitalizations.

Sponsors & Collaborators

• Sisli Hamidiye Etfal Training and Research Hospital: lead

Study Sites (1)

Sisli Hamidiye Etfal Training and Researching Hospital

Istanbul, Sarıyer, 34396, Turkey (Türkiye)

Location

Related Publications (3)

• Snowden C, Prentis J. Anesthesia for hepatobiliary surgery. Anesthesiol Clin. 2015 Mar;33(1):125-41. doi: 10.1016/j.anclin.2014.11.008. Epub 2014 Dec 31.

  PMID: 25701932 BACKGROUND

• Hemmerling TM. Pain management in abdominal surgery. Langenbecks Arch Surg. 2018 Nov;403(7):791-803. doi: 10.1007/s00423-018-1705-y. Epub 2018 Oct 3.

  PMID: 30284029 BACKGROUND

• von der Forst M, Weiterer S, Dietrich M, Loos M, Lichtenstern C, Weigand MA, Siegler BH. [Perioperative fluid management in major abdominal surgery]. Anaesthesist. 2021 Feb;70(2):127-143. doi: 10.1007/s00101-020-00867-7. German.

  PMID: 33034685 BACKGROUND

Study Design

• Study Type: observational
• Observational Model: OTHER
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Doctor

Study Record Dates

• First Submitted: August 16, 2023
• First Posted: August 21, 2023
• Study Start: August 1, 2023
• Primary Completion: September 20, 2023
• Study Completion: September 30, 2023
• Last Updated: August 21, 2023

Record last verified: 2023-08

Data Sharing

• IPD Sharing: Will not share

Locations

TU (1)