Coriandrum Sativum Seeds Improve Memory, Alleviate Anxiety and Depression, and Enhance Sleep Quality in University Students: A Randomized Controlled Trial

NCT05999071 | Completed

• 1 other identifier: 21/6/2022/2023
• Study Type: interventional
• Target: 86
• Locations: 1 country
• Sites: 1

Brief Summary

C. sativum could potentially serve as a memory enhancer for university students. It is considered a preferable option to stimulant drugs due to its safety profile. Additionally, C. sativum may have positive effects on anxiety, depression, and sleep quality. However, it is important to note that the current body of research on the effects of oral C. sativum on the brain and nervous system is limited, and further studies are necessary to fully understand its potential benefits. Thus, this study aims to assess the impact of oral C. sativum on memory performance, anxiety, depression, and sleep quality in university students.

Conditions

Memory Disorders; Anxiety Depression; Sleep

Keywords

Coriandrum sativum; memory performance; anxiety; depression; sleep

Outcome Measures

Primary Outcomes (1)

• Memory performance

  Prospective and Retrospective Memory Questionnaire was performed

  30 days

Secondary Outcomes (2)

• Anxiety and depression

  30 days

• Sleep quality

  30 days

Study Arms (2)

Coriandrum sativum group

EXPERIMENTAL

500 mg of C. sativum (capsules) were administered twice daily

Dietary Supplement: Coriandrum sativum seeds

control group

PLACEBO COMPARATOR

500 mg of starch (capsules) were administered twice daily

Dietary Supplement: Coriandrum sativum seeds

Interventions

Coriandrum sativum seeds DIETARY_SUPPLEMENT

Each group consisted of 50 students. In the C. sativum group, dried powdered seeds of C. sativum were administered, while in the control group, starch was provided as a placebo. Both the C. sativum and placebo capsules were identical in shape, color, and outer packaging to maintain the blinding of the participants.

Also known as: Coriandrum

Coriandrum sativum group; control group

Eligibility Criteria

• Age: 19 Years - 23 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Male or female university Student.
• of age

You may not qualify if:

• Medical diseases.
• Psychiatric disorders.
• Using any form of medication (including complementary and alternative medicines).
• Pregnant and lactating individuals.

Sponsors & Collaborators

• The Hashemite University: lead

Study Sites (1)

Faculty of Pharmaceutical Sciences

Zarqa, 13133, Jordan

Location

MeSH Terms

Conditions

Memory Disorders; Anxiety Disorders; Depression

Interventions

coriander oil

Condition Hierarchy (Ancestors)

Neurobehavioral Manifestations; Neurologic Manifestations; Nervous System Diseases; Signs and Symptoms; Pathological Conditions, Signs and Symptoms; Mental Disorders; Behavioral Symptoms; Behavior

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: TRIPLE
• Who Masked: PARTICIPANT, CARE PROVIDER, INVESTIGATOR
• Purpose: SUPPORTIVE CARE
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assisstant professor

Study Record Dates

• First Submitted: August 3, 2023
• First Posted: August 21, 2023
• Study Start: March 1, 2022
• Primary Completion: July 1, 2022
• Study Completion: July 1, 2022
• Last Updated: August 21, 2023

Record last verified: 2023-08

Data Sharing

• IPD Sharing: Will not share

Locations

JO (1)