Older Adults' Readiness to Stop Prescribed Medications

NCT05996237 | Completed

• 1 other identifier: STUDY23060137
• Study Type: observational
• Target: 108
• Locations: 1 country
• Sites: 1

Brief Summary

Polypharmacy, regular use of 5+ prescribed medications, is common among older adults and potentially harmful. Patients differ in their concern about medications, comfort in raising questions about them, and trust and confidence in physician judgment. This pilot observational research will determine older adults' readiness to "deprescribe," that is, stop prescribed medications under physician guidance.

Conditions

Polypharmacy, Decision-making

Outcome Measures

Primary Outcomes (1)

• Patient Motivation to Deprescribe

  Self-report measure (Linsky 2020): range 1-5; high scores = greater readiness to deprescribe; mean (SD) in VA sample 2.99 (0.80)

  Change over 6 months

Secondary Outcomes (1)

• Self-reported stopping/changing prescription medication

  6 months

Study Arms (1)

Registry participants

Participants in the University of Pittsburgh Claude D. Pepper Center community research registry. Potential participants will have stable regimens of 5+ prescribed medications and recent physician contact but no hospitalization in the prior 6 months.

Eligibility Criteria

• Age: 65 Years+
• Sex: all
• Healthy Volunteers: No
• Age Groups: Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Participants in the University of Pittsburgh Claude D. Pepper communty research registry.

You may qualify if:

• years or older
• Medical visit within past 6 months
• Self-report of at least 5 regular medications for at least 4 weeks

You may not qualify if:

• Diagnosis of dementia or score \<=4 on Memory Impairment Screen
• Hospitalization in prior 30 days with change in medications

Sponsors & Collaborators

• University of Pittsburgh: lead

Study Sites (1)

University of Pittsburgh

Pittsburgh, Pennsylvania, 15261, United States

Location

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Target Duration: 6 Months
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor

Study Record Dates

• First Submitted: August 9, 2023
• First Posted: August 18, 2023
• Study Start: September 21, 2023
• Primary Completion: December 31, 2024
• Study Completion: December 31, 2024
• Last Updated: January 9, 2025

Record last verified: 2025-01

Data Sharing

• IPD Sharing: Will share
• Shared Documents: STUDY PROTOCOL, SAP, ICF, ANALYTIC CODE
• Time Frame: After 6/1/25, available for 2 years
• Access Criteria: Written request to investigator

Locations

US (1)