NCT05995756

Brief Summary

From Jan 2022 to June 2022, 120 subjects (22-75 years of age, mean ±standard deviation \[SD\] of 53.20 ±14.49 years) with type 1 or type 2 diabetes participated in the study in P.R. China. Subjects wore two sensors in the abdomen which were paired with smart devices running a glucose monitoring mobile application (i3/H3 CGM APP). Subjects were asked to undergo one in-clinic visit (on one of the study days 2, 7-9, or 15) for 7-hour long YSI frequent sampling test (FST) periods, where intravenous (IV) blood samples were drawn every 15 min and analyzed using the YSI 2300 STAT Plus Glucose \& Lactate Analyzer (Yellow Springs Instrument, YSI Life Sciences, Yellow Springs, OH).

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
120

participants targeted

Target at P50-P75 for all trials

Timeline
Completed

Started Dec 2021

Shorter than P25 for all trials

Geographic Reach
1 country

3 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

December 20, 2021

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 30, 2022

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

June 30, 2022

Completed
1.1 years until next milestone

First Submitted

Initial submission to the registry

August 9, 2023

Completed
7 days until next milestone

First Posted

Study publicly available on registry

August 16, 2023

Completed
Last Updated

September 1, 2023

Status Verified

August 1, 2023

Enrollment Period

6 months

First QC Date

August 9, 2023

Last Update Submit

August 29, 2023

Conditions

Outcome Measures

Primary Outcomes (1)

  • overall mean absolute relative difference (MARD)

    8 or 15 days

Study Arms (2)

In pateint

Out pateint

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Adult (Aged ≥18) TD1 and TD2

You may qualify if:

  • Aged ≥18 years, male or female;
  • Clinically diagnosed with diabetes;
  • Being willing to wear the investigational device for the duration set according to its service life, and conduct glucose monitoring;
  • Consent to participate in this clinical study, and sign the Informed Consent Form (ICF).

You may not qualify if:

  • Disagree to wear the investigational device continuously according to the requirements of the trial;
  • Refuse venous blood collection for 7 consecutive hours (every 15 minutes) on a certain day during the trial;
  • Plan to undergo magnetic resonance imaging (MRI) during the clinical trial;
  • With diffuse subcutaneous nodules at the wearing site of the investigational device;
  • Have a history of diabetic ketoacidosis or hyperosmolar hyperglycemic state within the 6 months prior to screening;
  • With mental disorders, lack of self-control and inability to express clearly;
  • Have participated in any other clinical trial within the past 1 month;
  • Where the investigator thinks not suitable for being enrolled.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (3)

Beijing Pinggu Hospital

Beijing, China

Location

Peking University People's Hospital

Beijing, China

Location

The Second Xiangya Hospital of Central South University

Changsha, China

Location

MeSH Terms

Conditions

Diabetes Mellitus, Type 2

Condition Hierarchy (Ancestors)

Diabetes MellitusGlucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System Diseases

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

August 9, 2023

First Posted

August 16, 2023

Study Start

December 20, 2021

Primary Completion

June 30, 2022

Study Completion

June 30, 2022

Last Updated

September 1, 2023

Record last verified: 2023-08

Data Sharing

IPD Sharing
Will not share

Locations