NCT05993260

Brief Summary

This study is a nationwide randomised controlled trial (RCT) to test the impact of behavioural science-informed text messages notifying patients of their eligibility for the COVID-19 vaccine on vaccination rates.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
1,825,937

participants targeted

Target at P75+ for not_applicable

Timeline
Completed

Started Apr 2021

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

April 26, 2021

Completed
3 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 29, 2021

Completed
11 days until next milestone

Study Completion

Last participant's last visit for all outcomes

May 10, 2021

Completed
2.3 years until next milestone

First Submitted

Initial submission to the registry

August 11, 2023

Completed
4 days until next milestone

First Posted

Study publicly available on registry

August 15, 2023

Completed
Last Updated

August 15, 2023

Status Verified

August 1, 2023

Enrollment Period

3 days

First QC Date

August 11, 2023

Last Update Submit

August 11, 2023

Conditions

Outcome Measures

Primary Outcomes (1)

  • Booking rate within 72 hours

    The proportion of first dose vaccination appointments booked through the NHS National Booking System within 72 hours (inclusive) of the text message being sent

    72 hours

Secondary Outcomes (1)

  • Vaccination rate within 14 days

    14 days

Study Arms (8)

Control

ACTIVE COMPARATOR

Received the text message "You are now eligible for your free NHS Covid-19 vaccine. Please book yours now at \[LINK\] or by calling 119."

Behavioral: Control

Simple

EXPERIMENTAL

Received the text message "You can now book your free NHS Covid-19 vaccine. Please book yours now at \[LINK\] or by calling 119."

Behavioral: Behavioural science-informed text messages

Reserved

EXPERIMENTAL

Received the text message "Your free NHS Covid-19 vaccine is waiting for you. Please book yours now at \[LINK\] or by calling 119."

Behavioral: Behavioural science-informed text messages

Top of queue

EXPERIMENTAL

Received the text message "You've reached the top of the queue and are a priority for getting a free NHS Covid-19 vaccine. Please book yours now at \[LINK\] or by calling 119."

Behavioral: Behavioural science-informed text messages

Join the millions

EXPERIMENTAL

Received the text message "You are now eligible for your free NHS Covid-19 vaccine. Join the millions who have already had theirs. Please book yours now at \[LINK\] or by calling 119."

Behavioral: Behavioural science-informed text messages

Convenience

EXPERIMENTAL

Received the text message "You are now eligible for your free NHS Covid-19 vaccine. Choose a time and place that suits you. Please book yours now at \[LINK\] or by calling 119."

Behavioral: Behavioural science-informed text messages

Protection against virus

EXPERIMENTAL

Received the text message "You are now eligible for your free NHS Covid-19 vaccine. Getting vaccinated is the best protection against coronavirus. Please book yours now at \[LINK\] or by calling 119."

Behavioral: Behavioural science-informed text messages

Protect you and those close to you

EXPERIMENTAL

Received the text message "You are now eligible for your free NHS Covid-19 vaccine. Getting the vaccine is the best way to protect yourself and those close to you against coronavirus. Please book yours now at \[LINK\] or by calling 119."

Behavioral: Behavioural science-informed text messages

Interventions

Behaviourally-informed content in vaccination eligibility reminder text messages

ConvenienceJoin the millionsProtect you and those close to youProtection against virusReservedSimpleTop of queue
ControlBEHAVIORAL

Control vaccination eligibility reminder text message

Control

Eligibility Criteria

Age40 Years - 44 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • (i) satisfying the age criteria as defined above;
  • (ii) recorded in the National Immunisation Management System (NIMS);
  • (iii) with a valid mobile phone number;
  • (iv) who had not already received or been invited for the COVID-19 vaccine via NIMS at the time of the study.

You may not qualify if:

  • Participants with invalid phone numbers

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

NHS England

London, SE1 8UG, United Kingdom

Location

MeSH Terms

Conditions

Vaccination HesitancyCOVID-19

Condition Hierarchy (Ancestors)

Vaccination RefusalTreatment RefusalTreatment Adherence and ComplianceHealth BehaviorBehaviorPneumonia, ViralPneumoniaRespiratory Tract InfectionsInfectionsVirus DiseasesCoronavirus InfectionsCoronaviridae InfectionsNidovirales InfectionsRNA Virus InfectionsLung DiseasesRespiratory Tract Diseases

Study Officials

  • Hannah Behrendt, PhD

    The Behavioural Insights Team

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, CARE PROVIDER
Purpose
PREVENTION
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Director

Study Record Dates

First Submitted

August 11, 2023

First Posted

August 15, 2023

Study Start

April 26, 2021

Primary Completion

April 29, 2021

Study Completion

May 10, 2021

Last Updated

August 15, 2023

Record last verified: 2023-08

Data Sharing

IPD Sharing
Will share

All data requests should be submitted to NHS England and NHS Improvement (the data controller) for consideration. Access to the raw anonymised data may be granted for non-commercial research at the discretion of NHS England and NHS Improvement. Further information can be obtained from the corresponding author at hannah.behrendt@bi.team. Custom code that supports the findings of this study is available from the corresponding author upon request.

Shared Documents
STUDY PROTOCOL, ANALYTIC CODE

Locations