NCT05990647

Brief Summary

Purpose of study is to assess perioperative functional parameters of the anterior abdominal wall muscles and postural control status in patients with large and giant incisional hernias in a controlled diagnostic study. The study involved 95 patients (100% completed) with a large or giant incisional hernia of the anterior abdominal wall. The participants were divided into three groups by type of hernia repair: bridged hernia repair, Rives-Stoppa procedure, or TAR technique. Perioperative functional parameters of the anterior abdominal wall muscles were assessed by tension dynamometry. The postural balance assessments were made by raster photostereography.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
95

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started Jan 2018

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 2, 2018

Completed
5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2022

Completed
5 months until next milestone

Study Completion

Last participant's last visit for all outcomes

May 15, 2023

Completed
2 months until next milestone

First Submitted

Initial submission to the registry

July 22, 2023

Completed
23 days until next milestone

First Posted

Study publicly available on registry

August 14, 2023

Completed
Last Updated

August 14, 2023

Status Verified

August 1, 2023

Enrollment Period

5 years

First QC Date

July 22, 2023

Last Update Submit

August 6, 2023

Conditions

Keywords

incisional herniatension dynamometryraster photostereographypostural balancehernia repairbridging techniqueRives-StoppaTAR

Outcome Measures

Primary Outcomes (1)

  • Diagnostic accuracy

    Sensitivity and specificity

    1-2 weeks before surgical treatment and 6 months after reconstructive hernioplasty of postoperative ventral hernia

Study Arms (3)

Group I

ACTIVE COMPARATOR

32 patients who underwent classic abdominal wall anterior components separation and bridged hernia repair.

Diagnostic Test: Dynamometric tension assessmentDiagnostic Test: Postural balanceDiagnostic Test: Assessment of the hernia defect sizeDiagnostic Test: Physical activity of patients

Group II

ACTIVE COMPARATOR

34 patients who underwent posterior components separation with the internal oblique myofascial release by Rives-Stoppa

Diagnostic Test: Dynamometric tension assessmentDiagnostic Test: Postural balanceDiagnostic Test: Assessment of the hernia defect sizeDiagnostic Test: Physical activity of patients

Group III

ACTIVE COMPARATOR

29 patients who underwent posterior components separation with transversus abdominis release (TAR).

Diagnostic Test: Dynamometric tension assessmentDiagnostic Test: Postural balanceDiagnostic Test: Assessment of the hernia defect sizeDiagnostic Test: Physical activity of patients

Interventions

Tension dynamometry was carried out using the "Back-Check 600" diagnostic complex by Dr.WOLFF® (GmbH, Germany). The dynamometric stress assessment included tasks for flexion and extension of the body. The functional assessment of the abdominal wall muscles was assessed when preparing the patient for surgery (1-10 days before AWR-abdominal wall reconstruction) and 6 months after AWR.

Also known as: DT
Group IGroup IIGroup III
Postural balanceDIAGNOSTIC_TEST

Postural balance was assessed using raster photostereography and baropodometry on the "DIERS" diagnostic complex by Formetric-4D (GmbH, Germany). When analyzing the topography of the optical field, muscle imbalance is revealed in the form of lateral deviation and inclination of the trunk and pelvis, as well as the values of the angle of kyphosis and lordosis. When conducting baropodometry, the level of displacement of the pressure area on the feet of patients in a static and dynamic position was assessed. Diagnosis of postural balance in patients with incisional ventral hernia was performed a few days before surgical treatment and 6 months after AWR.

Also known as: PB
Group IGroup IIGroup III

Parameters of the hernial defect, including the volume of the hernial sac, the diameter of the hernial orifice, the ratio of hernia volume to the abdominal cavity volume, were performed using preoperative (1-10 days before AWR) multispiral computed tomography on a GE "BrightSpeed 16" tomograph (General Electric©, USA)

Group IGroup IIGroup III

To analyze the physical activity of patients, the measurement of the number of steps was used. The measurements of steps and the amount of distance traveled were carried out using a physical activity monitor - a fitness bracelet "MiBAND" (China). Measurements were taken 10 days before AWR and within 6 months after AWR.

Also known as: PAP
Group IGroup IIGroup III

Eligibility Criteria

Age18 Years - 75 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • big and giant incisional hernia
  • hernia without recurrence
  • age 18-75

You may not qualify if:

  • acute infection diseases
  • cancer
  • orthopedic diseases
  • terminal status
  • BMI\>39,9

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Republican specialized scientific practical medical center of surgery named after V.V. Vakhidov

Tashkent, 100100, Uzbekistan

Location

MeSH Terms

Conditions

Incisional Hernia

Interventions

Postural Balance

Condition Hierarchy (Ancestors)

HerniaPathological Conditions, AnatomicalPathological Conditions, Signs and SymptomsPostoperative ComplicationsPathologic Processes

Intervention Hierarchy (Ancestors)

ProprioceptionVestibulocochlear Physiological PhenomenaPhysiological PhenomenaMusculoskeletal Physiological PhenomenaMusculoskeletal and Neural Physiological PhenomenaSensationNervous System Physiological Phenomena

Study Officials

  • Otabek J. Eshonkhodjaev, MD, PhD

    Republican specialiazed scientific practical medical center of surgery named after V.V. Vakhidov

    STUDY CHAIR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
INVESTIGATOR
Purpose
DIAGNOSTIC
Intervention Model
PARALLEL
Model Details: Cohort study
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal investigator

Study Record Dates

First Submitted

July 22, 2023

First Posted

August 14, 2023

Study Start

January 2, 2018

Primary Completion

December 31, 2022

Study Completion

May 15, 2023

Last Updated

August 14, 2023

Record last verified: 2023-08

Data Sharing

IPD Sharing
Will share
Shared Documents
STUDY PROTOCOL, SAP, ICF, CSR

Locations