NCT05989178

Brief Summary

The purpose of this Registry is to prospectively collect data of Recurrent Pregnancy Loss (RPL) patients attending the specialized care centre at the BC Women's Hospital, in order to evaluate investigation practices, treatment options, and outcomes for this patient population over time.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
3,000

participants targeted

Target at P75+ for all trials

Timeline
81mo left

Started Jul 2022

Longer than P75 for all trials

Geographic Reach
1 country

1 active site

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress36%
Jul 2022Dec 2032

Study Start

First participant enrolled

July 12, 2022

Completed
1.1 years until next milestone

First Submitted

Initial submission to the registry

August 3, 2023

Completed
11 days until next milestone

First Posted

Study publicly available on registry

August 14, 2023

Completed
9.4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2032

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2032

Last Updated

December 13, 2024

Status Verified

December 1, 2024

Enrollment Period

10.5 years

First QC Date

August 3, 2023

Last Update Submit

December 9, 2024

Conditions

Keywords

Recurrent pregnancy lossUnexplainedExplainedMiscarriageLive Birth

Outcome Measures

Primary Outcomes (1)

  • Live Birth

    Percent of patients with a live birth within 5 years after initial visit at the clinic.

    5 years

Interventions

Follow-up questionnaires sent every year for the 5 years following the patient's initial visit.

Eligibility Criteria

Age15 Years - 49 Years
Sexfemale
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64)
Sampling MethodNon-Probability Sample
Study Population

Patients at the BC Women's Recurrent Pregnancy Loss Clinic seen for recurrent pregnancy loss.

You may qualify if:

  • Patients seen at the BC Women's Recurrent Pregnancy Loss Clinic with recurrent pregnancy loss, defined as ≥2 pregnancy losses before 20 weeks of gestation.

You may not qualify if:

  • Patients at BC Women's Recurrent Pregnancy Loss Clinic seen for reasons other than recurrent pregnancy loss.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

BC Women's Hospital & Health Centre

Vancouver, British Columbia, V6H 3N1, Canada

RECRUITING

Biospecimen

Retention: SAMPLES WITH DNA

Products of conception (optional)

MeSH Terms

Conditions

Abortion, Spontaneous

Interventions

Routinely Collected Health Data

Condition Hierarchy (Ancestors)

Pregnancy ComplicationsFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital Diseases

Intervention Hierarchy (Ancestors)

Health Care SurveysHealth Services ResearchHealth PlanningHealth Care Economics and OrganizationsHealth Care Quality, Access, and Evaluation

Study Officials

  • Mohamed A. Bedaiwy, MD, PhD

    BC Women's Hospital & Health Centre

    PRINCIPAL INVESTIGATOR

Central Study Contacts

Mohamed A. Bedaiwy, MD, PhD

CONTACT

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Target Duration
5 Years
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator, Professor and Head Division of Reproductive Endocrinology and Infertility, Department of Obstetrics and Gynaecology, University of British Columbia

Study Record Dates

First Submitted

August 3, 2023

First Posted

August 14, 2023

Study Start

July 12, 2022

Primary Completion (Estimated)

December 31, 2032

Study Completion (Estimated)

December 31, 2032

Last Updated

December 13, 2024

Record last verified: 2024-12

Data Sharing

IPD Sharing
Will not share

Locations