Investıgatıon of The Effıciency of Pulsed Electromagnetıc Field Therapy and Stretching Exercises
Investigation of The Efficiency of Pulsed Electromagnetic Field Treatment and Stretching Exercise In Experimental Skeletal Muscle Injury Model
1 other identifier
interventional
64
1 country
1
Brief Summary
In this study, a total of 69 Wistar Albino rats were used, five of which were in the preliminary study. The preliminary study was planned to determine the ideal PEMF treatment time. In the study, animals were divided into 5 groups (Control, INJ, INJ+Exercise, INJ+PEMF, INJ+Exercise+PEMF). Experimental animals were sacrificed on the 7th and 14th days to see the effects of the treatments. At the end of the experiment, genetic, histopathological, and immunohistochemical evaluations were made in the muscle tissue.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for not_applicable
Started Sep 2022
Shorter than P25 for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
September 5, 2022
CompletedPrimary Completion
Last participant's last visit for primary outcome
October 2, 2022
CompletedStudy Completion
Last participant's last visit for all outcomes
November 7, 2022
CompletedFirst Submitted
Initial submission to the registry
August 4, 2023
CompletedFirst Posted
Study publicly available on registry
August 14, 2023
CompletedAugust 14, 2023
August 1, 2023
27 days
August 4, 2023
August 4, 2023
Conditions
Keywords
Outcome Measures
Primary Outcomes (3)
Mononuclear cell infiltration, Atrophy and necrosis, Pyknotic nucleus assesment at the end of two weeks
hematoxylin-eosin staining
two week
VEGF and FGF assesment at the end of two weeks
immunohischemical staining
two week
TGF-β1, eNOS assesment at the end of two weeks
Quantitative Reverse-Transcriptase Polymerase Chain Reaction (RT-qPCR)
two week
Study Arms (4)
Control
NO INTERVENTIONStretching Exercise
EXPERIMENTALPulsed Electromagnetic Field
EXPERIMENTALPulsed Electromagnetic Field and Stretching Exercise
EXPERIMENTALInterventions
5 day/week, two week, one session stretching exercises consisting of ten repetitions of one minute
5 day/week, two week,two sessions consisting of 180 minutes
Eligibility Criteria
You may qualify if:
- Healthy young wistar albino rats
You may not qualify if:
- not having any injury
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
SuleymanDU
Isparta, Turkey (Türkiye)
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Intervention Hierarchy (Ancestors)
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- TREATMENT
- Intervention Model
- SINGLE GROUP
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Assistant Professor
Study Record Dates
First Submitted
August 4, 2023
First Posted
August 14, 2023
Study Start
September 5, 2022
Primary Completion
October 2, 2022
Study Completion
November 7, 2022
Last Updated
August 14, 2023
Record last verified: 2023-08
Data Sharing
- IPD Sharing
- Will not share