Utilizing Advocates and Supporters to Increase Lung Cancer Screening Rates in Eligible Participants

NCT05978128 | Recruiting

• 2 other identifiers: 22-000947NCI-2023-04133
• Study Type: interventional
• Target: 800
• Locations: 1 country
• Sites: 1

Brief Summary

This clinical trial assesses the use of advocates and supporters of breast and lung cancer screening to increase lung cancer screening rates amongst eligible participants. Imaging-based cancer screening is utilized with variable frequency. Breast cancer screening with mammography has been widely accepted and is commonly used among eligible women. Lung screening with computed tomography scans is poorly used, despite the potential to decrease deaths from lung cancer. There are many reasons lung screening isn't being used when compared to breast screening, such as smoking stigma and fear, along with a lack of awareness of lung screening. By conducting this trial, researchers want to assess the effectiveness of advocates and supporters of breast and lung screening, and to learn about the psychological barriers to cancer screening, identifying those that are unique to lung screening.

Conditions

Breast Carcinoma; Lung Carcinoma

Outcome Measures

Primary Outcomes (1)

• Increased rates of lung and breast cancer screening adherence

  By following up with patients over the defined study period and assessing whether they obtained an incidence screen completed at one-year +/- 3 months from the recommended time. Will also measure the rates of survey completion by consented participants, the number of clicks and time spent reviewing educational materials, and the number of new participants who contacted the program through a referral by another participant.

  Up to 3 years

Secondary Outcomes (1)

• Success of "sphere of influence" model

  Up to 3 years

Study Arms (1)

Screening (electronic patient portal, patient navigation)

EXPERIMENTAL

Participants access an electronic patient portal with educational materials at baseline, 1- and 2-year follow-ups, and also interact with a patient navigator on study. Patients also receive materials to share with their friends/family on benefits of breast and lung cancer screening on study.

Behavioral: Health Education; Other: Health Promotion and Education; Behavioral: Patient Navigation; Other: Survey Administration

Interventions

Health Education BEHAVIORAL

Access electronic patient portal with educational material

Screening (electronic patient portal, patient navigation)

Health Promotion and Education OTHER

Receive materials on breast/lung cancer screening

Screening (electronic patient portal, patient navigation)

Patient Navigation BEHAVIORAL

Interact with a patient navigator

Also known as: Patient Navigator Program

Screening (electronic patient portal, patient navigation)

Survey Administration OTHER

Ancillary studies

Screening (electronic patient portal, patient navigation)

Eligibility Criteria

• Age: 40 Years - 80 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Age:
• Breast screening \> 40
• Lung screening 50-80
• Male (M) or Female (F)
• Current, former, or never smokers
• Close family or friend with smoking history (in or out of state)

You may not qualify if:

• Age:
• Breast screening \< 40
• Lung screening \< 50 or \> 80
• Persons who had previously received a diagnosis of lung cancer, had hemoptysis, or had an unexplained weight loss of more than 6.8 kg (15 lb) in the preceding year will also be excluded
• Persons with an active cancer

Sponsors & Collaborators

• Jonsson Comprehensive Cancer Center: lead

Study Sites (1)

UCLA / Jonsson Comprehensive Cancer Center

Los Angeles, California, 90095, United States

RECRUITING

MeSH Terms

Conditions

Breast Neoplasms; Lung Neoplasms

Interventions

Health Promotion; Educational Status; Patient Navigation

Condition Hierarchy (Ancestors)

Neoplasms by Site; Neoplasms; Breast Diseases; Skin Diseases; Skin and Connective Tissue Diseases; Respiratory Tract Neoplasms; Thoracic Neoplasms; Lung Diseases; Respiratory Tract Diseases

Intervention Hierarchy (Ancestors)

Health Education; Preventive Health Services; Health Services; Health Care Facilities Workforce and Services; Socioeconomic Factors; Population Characteristics; Patient-Centered Care; Primary Health Care; Comprehensive Health Care; Patient Care Management; Health Services Administration

Study Officials

• Ashley E Prosper

  UCLA / Jonsson Comprehensive Cancer Center

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: SCREENING
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 28, 2023
• First Posted: August 7, 2023
• Study Start: July 28, 2023
• Primary Completion (Estimated): September 30, 2028
• Study Completion (Estimated): September 30, 2029
• Last Updated: November 10, 2025

Record last verified: 2025-11

Locations

US (1)