NCT05977751

Brief Summary

Prospective, multi-center, international, unblinded, single-arm trial of subjects undergoing FemBloc followed by ultrasound confirmation test.

Trial Health

77
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
573

participants targeted

Target at P75+ for not_applicable

Timeline
61mo left

Started Oct 2023

Longer than P75 for not_applicable

Geographic Reach
1 country

8 active sites

Status
recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress33%
Oct 2023Jun 2031

First Submitted

Initial submission to the registry

July 27, 2023

Completed
8 days until next milestone

First Posted

Study publicly available on registry

August 4, 2023

Completed
3 months until next milestone

Study Start

First participant enrolled

October 31, 2023

Completed
6.1 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2029

Expected
1.5 years until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2031

Last Updated

March 3, 2026

Status Verified

March 1, 2026

Enrollment Period

6.1 years

First QC Date

July 27, 2023

Last Update Submit

March 1, 2026

Conditions

Keywords

Permanent Birth ControlPermanent ContraceptionPermanent Sterilization

Outcome Measures

Primary Outcomes (1)

  • Pregnancy Rate

    Number of subjects who were told to rely on FemBloc for birth control and became pregnant through one (1) year.

    one (1) year

Secondary Outcomes (2)

  • Reliance Rate

    ninety (90) days post treatment

  • Long term Pregnancy Rate

    Five (5) years

Study Arms (1)

FemBloc

EXPERIMENTAL

Investigational device and procedure

Device: FemBloc

Interventions

FemBlocDEVICE

Treatment for women who desire non-surgical permanent birth control by occlusion of the fallopian tubes.

FemBloc

Eligibility Criteria

Age21 Years - 50 Years
Sexfemale(Gender-based eligibility)
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Female, 21 - 50 years of age desiring permanent birth control.
  • Sexually active with male partner.
  • Regular menstrual cycle for last 3 months or on hormonal contraceptives.

You may not qualify if:

  • Uncertainty about the desire to end fertility.
  • Known or suspected pregnancy.
  • Prior tubal surgery, including sterilization attempt.
  • Presence, suspicion, or previous history of gynecologic malignancy.
  • Scheduled to undergo concomitant intrauterine procedures (i.e. endometrial ablation) at the time of either FemBloc Treatment or prior to final confirmation test.
  • Abnormal uterine bleeding requiring evaluation or treatment.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (8)

New Horizons Clinical Trials

Chandler, Arizona, 85224, United States

RECRUITING

Stanford University

Palo Alto, California, 94304, United States

RECRUITING

University of California Davis

Sacramento, California, 95817, United States

RECRUITING

Midtown OB GYN North

Columbus, Georgia, 31909, United States

RECRUITING

Rosemark WomenCare Specialists

Idaho Falls, Idaho, 83404, United States

RECRUITING

Maimonides Medical Center

Brooklyn, New York, 11219-2919, United States

RECRUITING

Seven Hills Women's Health Centers

Cincinnati, Ohio, 45242, United States

RECRUITING

University of Utah

Salt Lake City, Utah, 84108, United States

RECRUITING

Related Links

Study Officials

  • Study Sponsor

    Medical Affairs and Clinical Development

    STUDY DIRECTOR

Central Study Contacts

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
PREVENTION
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

July 27, 2023

First Posted

August 4, 2023

Study Start

October 31, 2023

Primary Completion (Estimated)

December 1, 2029

Study Completion (Estimated)

June 1, 2031

Last Updated

March 3, 2026

Record last verified: 2026-03

Locations