NCT05970458

Brief Summary

Cross-sectional comparative study of general and stoma-specific quality of life in patients with stoma in Addis Abeba, Ethiopia, and Stockholm, Sweden.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
66

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Oct 2022

Shorter than P25 for all trials

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

October 1, 2022

Completed
4 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 30, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 30, 2023

Completed
6 months until next milestone

First Submitted

Initial submission to the registry

July 24, 2023

Completed
8 days until next milestone

First Posted

Study publicly available on registry

August 1, 2023

Completed
Last Updated

August 4, 2023

Status Verified

August 1, 2023

Enrollment Period

4 months

First QC Date

July 24, 2023

Last Update Submit

August 2, 2023

Conditions

Outcome Measures

Primary Outcomes (2)

  • General quality of life

    Overall health through visual analogue scale (VAS) from zero (the worst imaginable health) to 100 (the best imaginable health) from the European Quality of Life 5 Dimensions 5 Level Version (EQ5D-5L).

    October 2022 to Jan 2023

  • Stoma-specific quality of life

    The Stoma Quality of life questionnaire consists of 20 questions about stoma-specific aspects of quality of life where each variable is valued equally. Answers are graded in a four-point scale; 1: always, 2: sometimes, 3: rarely, and 4: not at all, with a maximum score of 80. The higher score the better QoL. To get a comparable overall result, the total score (range 20-80) can be converted to a zero to 100 score.

    October 2022 to Jan 2023

Secondary Outcomes (1)

  • Stoma complications

    October 2022 to Jan 2023

Study Arms (3)

Ethioperm

All patients with a permanent ostomy visiting the stoma center in Addis Abeba

Other: Quality of life assessment

EthioTemp

All patients waiting for ostomy reversal at Tikur Anbessa Specialized Hospital

Other: Quality of life assessment

SweSto

All patients visiting the stoma clinic at South General Hospital

Other: Quality of life assessment

Interventions

EQ5D-5L and Stoma QoL

EthioTempEthiopermSweSto

Eligibility Criteria

Age18 Years+
Sexall
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Adult patients (≥ 18 years old) with ileostomy or colostomy for more than two months, with willingness and ability to give informed consent

You may qualify if:

  • adult patients (≥ 18 years old)
  • having an ostomy for more than two months
  • willingness and ability to give informed consent

You may not qualify if:

  • non-intestinal stoma

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Tikur Anbessa Specialized Hospital

Addis Ababa, Ethiopia

Location

Related Publications (1)

  • Eklov K, Shiferaw A, Rosen A, Bekele S, Ayalew B; ACROSS Collaborative Group; Bringman S, Nygren J, Lofgren J, Everhov AH. Stoma-related complications and quality-of-life assessment: A cross-sectional study with patients from Ethiopia and Sweden. World J Surg. 2024 Jul;48(7):1739-1748. doi: 10.1002/wjs.12209. Epub 2024 May 14.

Study Officials

  • Åsa Everhov, MD PhD

    Karolinska Institutet

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
observational
Observational Model
ECOLOGIC OR COMMUNITY
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator, Ass professor

Study Record Dates

First Submitted

July 24, 2023

First Posted

August 1, 2023

Study Start

October 1, 2022

Primary Completion

January 30, 2023

Study Completion

January 30, 2023

Last Updated

August 4, 2023

Record last verified: 2023-08

Data Sharing

IPD Sharing
Will not share

Locations