Trials Sponsors Conditions Drugs Pricing

Conditions

Bladder Cancer Stage I

Outcome Measures

Primary Outcomes (1)

Impact of avoiding repeat resection on recurrence and progression free survival.
occurrence of new tumors or progression of the primary tumor will be compared between both groups. Tis will be assessed by both cystoscopy and MRI findings
12 month

Secondary Outcomes (1)

perioperative complications associated with re TURBT
12 month

Other Outcomes (1)

The financial cost associated with performing repeat resection.
12 months

Study Arms (2)

Re_TUR

Those patients diagnosed with pT1 after initial ERBT with negative vertical and horizontal safety margins will undergo second look as endorsed by the guidelines.

Behavioral: Avoid second resection after initial complete resection

No re_TUR

Those patients diagnosed with pT1 after initial ERBT with negative vertical and horizontal safety margins won't undergo second look as endorsed by the guidelines and will receive directly intravesical BCG

Behavioral: Avoid second resection after initial complete resection

Interventions

Avoid second resection after initial complete resectionBehavioral

Those patients diagnosed with pT1 after initial ERBT with negative vertical and horizontal safety margins won't undergo second look as endorsed by the guidelines.

No re_TURRe_TUR

Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.

Eligibility Criteria

Age18 Years - 80 Years

Sexall

Healthy VolunteersNo

Age GroupsAdult (18-64), Older Adult (65+)

Sampling MethodProbability Sample

Study Population

Male and female patients treated with ERBT and diagnosed with pT1 disease with negative vertical and horizontal safety margins at final pathology.

You may qualify if:

Patients treated with ERBT and diagnosed with pT1 disease with negative vertical and horizontal safety margins at final pathology.

Sponsors & Collaborators

Mansoura University
Otherlead

Study Sites (1)

Urology and nephrology center, Mansoura University

Al Mansurah, Dakahlia Governorate, 35516, Egypt

RECRUITING

Ahmed Mosbah, MDCONTACT01002275698 mosbah64@yahoo.com

Biospecimen

Retention: SAMPLES WITH DNA

Bladder tumor tissues resected during cystoscopy

MeSH Terms

Conditions

Urinary Bladder Neoplasms

Condition Hierarchy (Ancestors)

Urologic NeoplasmsUrogenital NeoplasmsNeoplasms by SiteNeoplasmsFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesUrinary Bladder DiseasesUrologic DiseasesMale Urogenital Diseases

Study Officials

Mahmoud Laymon, MD,MRCS
Urology &Nephrology Center, Mansoura University, Egypt
PRINCIPAL INVESTIGATOR

Central Study Contacts

Mahmoud Laymon, MD,MRCS

CONTACT

01002275698 dr_mahmoudlaymon@mans.edu.eg

Ahmed elassmy, MD

CONTACT

a_assmy@yahoo.com

Study Design

Study Type: observational
Observational Model: CASE CONTROL
Time Perspective: PROSPECTIVE
Sponsor Type: OTHER
Responsible Party: SPONSOR

Study Record Dates

First Submitted

July 3, 2023

First Posted

August 1, 2023

Study Start

July 1, 2023

Actual (reported)

Primary Completion

August 2025

Estimated (date passed)

This estimate has passed. The registry has not confirmed an actual date for this milestone.

Can Second Resection for pT1 Bladder Cancer be Avoided After Initial En-Bloc Resection With Negative Safety Margins

Brief Summary

Registry Overview

Trial Relationships

Study Timeline

Study Start

First Submitted

First Posted

Primary Completion

Study Completion

Conditions

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (1)

Other Outcomes (1)

Study Arms (2)

Re_TUR

No re_TUR

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

Biospecimen

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Study Officials

Central Study Contacts

Study Design

Study Record Dates

You may not qualify if:

Source record

Locations

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

Study Start

First Submitted

First Posted

Primary Completion

Study Completion

Conditions

Outcome Measures

Primary Outcomes (1)

Secondary Outcomes (1)

Other Outcomes (1)

Study Arms (2)

Re_TUR

No re_TUR

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

Biospecimen

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Study Officials

Central Study Contacts

Study Design

Study Record Dates

You may not qualify if:

Source record

Locations