Trials Sponsors Conditions Drugs Pricing

Conditions

Kidney Failure, Chronic

Keywords

ketoneacetoacetateacetate

Outcome Measures

Primary Outcomes (4)

Mean in kidney acetate uptake
Kidney acetate uptake measured by pet scan
30 minutes
Mean in kidney acetoacetate uptake
Kidney acetoacetate uptake measured by pet scan
30 minutes
Mean in kidney acetoacetate metabolism
Kidney acetoacetate metabolism measured by pet scan
30 minutes
Mean in kidney acetate metabolism
Kidney acetate metabolism measured by pet scan
30 minutes

Secondary Outcomes (1)

Mean in heart ejection fraction
30 minutes

Study Arms (1)

Chronic kidney failure

No interventions for the purpose of the study. They will simply undergo two PET scans consecutively

Radiation: PET scan metabolic day

Interventions

PET scan metabolic dayRadiation

11C-Acetate and 11C-Acetoacetate PET scans

Chronic kidney failure

Registry-reported names are shown in full. Names without a link have not yet been matched to a Syfrah profile.

Eligibility Criteria

Age18 Years+

Sexall

Healthy VolunteersNo

Age GroupsAdult (18-64), Older Adult (65+)

Sampling MethodProbability Sample

Study Population

People with kidney failure

You may qualify if:

BMI between 18.5 and 40

Sponsors & Collaborators

Nestle Health Science
Industrycollaborator
Université de Sherbrooke
Otherlead

Study Sites (1)

Centre de recherche sur le vieillissement

Sherbrooke, Quebec, J1H 4C4, Canada

MeSH Terms

Conditions

Kidney Failure, ChronicKetosis

Condition Hierarchy (Ancestors)

Renal Insufficiency, ChronicRenal InsufficiencyKidney DiseasesUrologic DiseasesFemale Urogenital DiseasesFemale Urogenital Diseases and Pregnancy ComplicationsUrogenital DiseasesMale Urogenital DiseasesChronic DiseaseDisease AttributesPathologic ProcessesPathological Conditions, Signs and SymptomsAcidosis

Study Officials

Mélanie Godin, MD
Université de Sherbrooke
PRINCIPAL INVESTIGATOR

Study Design

Study Type: observational
Observational Model: CASE ONLY
Time Perspective: PROSPECTIVE
Sponsor Type: OTHER
Responsible Party: SPONSOR

Study Record Dates

First Submitted

July 20, 2023

First Posted

August 1, 2023

Study Start

February 2, 2024

Actual (reported)

Primary Completion

December 15, 2026

Estimated

Planned date reported by the registry; this milestone is not confirmed as achieved.

Acetoacetate and Acetate Metabolism in Patients With Chronic Kidney Failure.(RENO-TEP)

Brief Summary

Registry Overview

Trial Relationships

Study Timeline

First Submitted

First Posted

Study Start

Primary Completion

Study Completion

Conditions

Keywords

Outcome Measures

Primary Outcomes (4)

Secondary Outcomes (1)

Study Arms (1)

Chronic kidney failure

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Study Officials

Study Design

Study Record Dates

You may not qualify if:

Data Sharing

Source record

Locations

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

First Submitted

First Posted

Study Start

Primary Completion

Study Completion

Conditions

Keywords

Outcome Measures

Primary Outcomes (4)

Secondary Outcomes (1)

Study Arms (1)

Chronic kidney failure

Interventions

Eligibility Criteria

You may qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Condition Hierarchy (Ancestors)

Study Officials

Study Design

Study Record Dates

You may not qualify if:

Data Sharing

Source record

Locations