Assessing Exclusive Breastfeeding Practice

NCT05959460 | Completed DMC

• 1 other identifier: RAS6073
• Study Type: observational
• Target: 206
• Locations: 0 countries
• Sites: N/A

Brief Summary

This study was a longitudinal design. The questionnaire on exclusive breastfeeding was administered and was validated against the deuterium oxide dose-to-mother technique to assess human milk intake of babies aged 3 and 6 mo.

Conditions

Exclusive Breastfeeding; Human Milk; Breast Milk

Outcome Measures

Primary Outcomes (2)

• Non-milk oral intake

  Quantity of non-milk oral intake (g)

  Jan 2016 - Dec 2020

• Human milk intake

  Quantity of milk intake (g)

  Jan 2016 - Dec 2020

Secondary Outcomes (9)

• Body composition of mothers: total body water

  Jan 2016 - Dec 2020

• Body composition of mothers: fat free mass

  Jan 2016 - Dec 2020

• Body composition of mothers: fat mass

  Jan 2016 - Dec 2020

• Weight of infants

  Jan 2016 - Dec 2020

• length of infants

  Jan 2016 - Dec 2020

Study Arms (1)

1

This is an observation study to determine exclusive breastfeeding practice. Mother-child pairs were enrolled at 3 months ± 7d and were followed-up at 6 months ± 7d. Questionnaire was administered. Then, baseline saliva samples were collected and deuterium oxide dose was administered. Then, post-dose saliva samples were collected.

Other: Deuterium dose-to-mother method for assessing breastfeeding

Interventions

Deuterium dose-to-mother method for assessing breastfeeding OTHER

Exclusive breastfeeding practice was compared between maternal recall and the deuterium dose-to-mother method.

1

Eligibility Criteria

• Age: 3 Months - 40 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Child (0-17), Adult (18-64)
• Sampling Method: Non-Probability Sample

Study Population

The participants were mother-baby pairs who were eligible according to the inclusion and exclusion criteria. There were recruited from hospitals, health clinics, or communities.

You may qualify if:

• Mother who practice exclusive breastfeeding
• Age of mother 18 - 40 years
• Parity: no more than 3
• Baby 3 month ± 7 days
• Nutritional status Weight-for-height Z score (WHZ) \> -2
• Full term baby (37 - 40 weeks)

You may not qualify if:

• Twin or more baby
• Low birth weight
• Baby with oedema
• Mother with fluid retention disease (kidney disease, heart disease, hypothyroidism)
• Smoking mother
• Drinking alcohol mother

Sponsors & Collaborators

• Mahidol University: lead
• Pakistan Institute of Nuclear Science and Technology (PINSTECH): collaborator
• Faculty of Medicine, University of Ruhuna, Sri Lanka: collaborator
• National Institute of Nutrition, Vietnam: collaborator
• International Centre for Diarrhoeal Disease Research, Bangladesh: collaborator
• International Atomic Energy Agency: collaborator
• St. John's Research Institute: collaborator
• National Institute of Health Research and Development, Ministry of Health Republic of Indonesia: collaborator
• Research Organization for Nuclear Energy-BRIN Indonesia: collaborator
• National University of Malaysia: collaborator
• National Center for Maternal and Child Health, Mongolia: collaborator

Related Publications (2)

• Tongchom W, Pongcharoen T, Judprasong K, Udomkesmalee E, Kriengsinyos W, Winichagoon P. Human Milk Intake of Thai Breastfed Infants During the First 6 Months Using the Dose-to-Mother Deuterium Dilution Method. Food Nutr Bull. 2020 Sep;41(3):343-354. doi: 10.1177/0379572120943092. Epub 2020 Aug 17.

  PMID: 32799695 BACKGROUND

• Mulol H, Coutsoudis A. Limitations of maternal recall for measuring exclusive breastfeeding rates in South African mothers. Int Breastfeed J. 2018 May 25;13:19. doi: 10.1186/s13006-018-0159-8. eCollection 2018.

  PMID: 29849742 BACKGROUND

Related Links

• https://www.iaea.org/publications/8168/stable-isotope-technique-to-assess-intake-of-human-milk-in-breastfed-infants

MeSH Terms

Conditions

Breast Feeding

Condition Hierarchy (Ancestors)

Feeding Behavior; Behavior

Study Officials

• Tippawan Pongcharoen, PhD

  Mahidol U

  STUDY DIRECTOR

Study Design

• Study Type: observational
• Observational Model: COHORT
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor Dr.

Study Record Dates

• First Submitted: July 16, 2023
• First Posted: July 25, 2023
• Study Start: January 1, 2016
• Primary Completion: December 31, 2018
• Study Completion: January 1, 2020
• Last Updated: April 2, 2024

Record last verified: 2024-03

Data Sharing

• IPD Sharing: Will not share