Effects of e-Cigarettes on Perceptions and Behavior - Remote Substudy # 2

NCT05958992 | Completed DMC

• 1 other identifier: Substudy #2: UP-20-00744
• Study Type: interventional
• Target: 461
• Locations: 1 country
• Sites: 1

Brief Summary

This study assess the ways in which e-cigarette product characteristics, such as flavors and nicotine salts, impact user experience to inform potential regulations.

Conditions

Electronic Cigarette Use; Cigarette Smoking; Cigarette Use, Electronic; Vaping

Keywords

vaping; e-cigarette; vape; nicotine; tobacco

Outcome Measures

Primary Outcomes (3)

• Subjective Appeal

  This self-report measures of subjective product appeal will be completed following e-cigarette self-administration. Scores can range from 0 to 100 for the appeal rating, with lower scores representing lower levels of appeal and higher scores representing higher levels of appeal.

  1 hour

• Sensory Attributes

  This self-report measures of product sensory attributes will be completed following e-cigarette self-administration. Scores can range from 0 to 100 for the sensory attribute rating, with lower scores representing lower levels of liking the sensory attribute and higher scores representing greater liking of the sensory attribute.

  1 hour

• Vaping Delay

  Minutes delayed before purchasing time to vape an e-liquid.

  1 hour

Study Arms (5)

E-Liquid 1

EXPERIMENTAL

Participants will self-administer an assigned e-liquid.

Other: E-cigarette

E-Liquid 2

EXPERIMENTAL

Participants will self-administer an assigned e-liquid.

Other: E-cigarette

E-liquid 3

EXPERIMENTAL

Participants will self-administer an assigned e-liquid.

Other: E-cigarette

E-liquid 4

EXPERIMENTAL

Participants will self-administer an assigned e-liquid.

Other: E-cigarette

No e-liquid

NO INTERVENTION

Participants will not receive an e-liquid to self-administer.

Interventions

E-cigarette OTHER

Participants will self-administer experimenter-provided e-cigarettes

E-Liquid 1; E-Liquid 2; E-liquid 3; E-liquid 4

Eligibility Criteria

• Age: 21 Years+
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Vapers/E-cigarette Users - Regular use of e-cigarettes/vaping devices containing nicotine
• Cigarette Smokers
• \- Regular use of cigarettes containing nicotine

You may not qualify if:

• Pregnant or planning to become pregnant

Sponsors & Collaborators

• University of Southern California: lead

Study Sites (1)

University of Southern California

Los Angeles, California, 90033, United States

Location

MeSH Terms

Conditions

Vaping; Cigarette Smoking

Interventions

Electronic Nicotine Delivery Systems

Condition Hierarchy (Ancestors)

Smoking; Behavior; Tobacco Smoking; Tobacco Use

Intervention Hierarchy (Ancestors)

Smoking Devices; Manufactured Materials; Technology, Industry, and Agriculture

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, INVESTIGATOR
• Purpose: OTHER
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Professor of Preventive Medicine

Model Details: Participants will be randomly assigned to use an e-liquid

Study Record Dates

• First Submitted: July 7, 2023
• First Posted: July 25, 2023
• Study Start: August 25, 2020
• Primary Completion: May 1, 2022
• Study Completion: May 1, 2022
• Last Updated: July 25, 2023

Record last verified: 2023-07

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)