Bowel Sounds Analysis in Paediatric Inflammatory Bowel Disease: Relationship With wPCDAI

NCT05955963 | Unknown

• 1 other identifier: PI2021_843_0018
• Study Type: interventional
• Target: 49
• Locations: 1 country
• Sites: 1

Brief Summary

The precise and noninvasive evaluation of disease activity among patients with Crohn's disease is not easy, especially for children. It deals with clinical, biological, histological and radiological parameters. Bowel sounds (BS) when evaluated by a stethoscope are modified by several factors including surgery, infection, drugs or intestinal inflammation. These factors can interact on intestinal motricity. There is a direct relationship between gastrointestinal motility and characteristics of BW. The study of BS using a stethoscope is a simple method, although operator dependent and subjective,with a wide inter and intraindividual variability. Some studies among adults showed interest in the spectral analysis of BS to assess gastrointestinal motility. This more precise and reproducible method is not operator dependent. To date, no such study has evaluated the correlation between disease activity and the spectral pattern of BS. of this project is to assess the correlation between disease activity and the spectral pattern of BS in pediatric Crohn's disease.

Conditions

Bowel Sounds; Intestinal Inflammation; Crohn Disease

Keywords

bowel sounds; Intestinal Inflammation; Crohn Disease

Outcome Measures

Primary Outcomes (3)

• evaluation of frequency of bowel sounds

  one day

• evaluation of wPCDAI

  wPCDAI is WEIGHTED PAEDIATRIC CROHN'S DISEASE ACTIVITY INDEX

  one day

• correlation between wPCDAI and frequency of bowel sounds

  wPCDAI is WEIGHTED PAEDIATRIC CROHN'S DISEASE ACTIVITY INDEX

  one day

Study Arms (1)

paediatric inflammatory bowel disease

EXPERIMENTAL

Other: Abdominal auscultation

Interventions

Abdominal auscultation OTHER

spectral analysis of Bowel sounds

paediatric inflammatory bowel disease

Eligibility Criteria

• Age: 4 Years - 17 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17)

You may qualify if:

• Crohn's Disease
• Age between 4 and 17 years
• Follow-up at CHU Amiens-Picardie

You may not qualify if:

• Other diseases than Crohn's or treatments affecting the gastrointestinal tract, recent (\< 3 months) surgery or refusal to participate (parents or children)

Sponsors & Collaborators

• Centre Hospitalier Universitaire, Amiens: lead

Study Sites (1)

CHU Amiens

Amiens, 80054, France

Location

MeSH Terms

Conditions

Crohn Disease

Condition Hierarchy (Ancestors)

Inflammatory Bowel Diseases; Gastroenteritis; Gastrointestinal Diseases; Digestive System Diseases; Intestinal Diseases

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: DIAGNOSTIC
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: July 13, 2023
• First Posted: July 21, 2023
• Study Start: June 24, 2021
• Primary Completion: September 2, 2023
• Study Completion: June 4, 2024
• Last Updated: July 21, 2023

Record last verified: 2023-07

Data Sharing

• IPD Sharing: Will not share

Locations

FR (1)