Thoracic Fluid Content for Weaning Parameters
Thoracic Fluid Content by Electrical Cardiometry Versus Diaphragmatic Excursion by Ultrasound for Prediction of Weaning Success in Patients With Lung Congestion
1 other identifier
observational
100
1 country
1
Brief Summary
The study aims to compare the thoracic fluid content measured by electrical cardiometry versus the diaphragmatic excursion measured by ultrasound for prediction of weaning success in patients having lung congestion.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started May 2023
Shorter than P25 for all trials
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
May 20, 2023
CompletedFirst Submitted
Initial submission to the registry
July 9, 2023
CompletedFirst Posted
Study publicly available on registry
July 17, 2023
CompletedPrimary Completion
Last participant's last visit for primary outcome
March 20, 2024
CompletedStudy Completion
Last participant's last visit for all outcomes
April 20, 2024
CompletedJuly 17, 2023
July 1, 2023
10 months
July 9, 2023
July 9, 2023
Conditions
Outcome Measures
Primary Outcomes (1)
Thoracic fluid content by electrical cardiometry versus diaphragmatic excursion by Ultrasound for prediction of weaning success in patients with lung congestion
compare the thoracic fluid content measured by electrical cardiometry versus the diaphragmatic excursion measured by ultrasound for prediction of weaning success in patients having lung congestion.
1 year
Eligibility Criteria
The study will be conducted on 100 patients admitted to critical care department at Benha university hospitals with lung congestion. Patients who are candidate for weaning from invasive mechanical ventilation (after 48 h) and who agree to participate in the study will be involved.
You may qualify if:
- Patients of both genders aged 18-70 years old.
- Acute Physiology and Chronic Health Evaluation II (APACHE II) score
- Patients with congested lung including; Acute exacerbation of COPD patients with acute respiratory failure (PaO2/FiO2 ratio ≤300 or PaCO2 ≥ 50 mm Hg at intubation), pneumonia, chronic kidney disease, heart failure (New York Heart Association Classification III, IV) who will be candidate for weaning from invasive mechanical ventilation according to the treating physician's judgement using the ICU weaning protocol.
You may not qualify if:
- Patients younger than 18 years or older than 70 years
- Refusal to participate.
- Obesity (BMI≥35).
- Pregnancy.
- Patients with pneumothorax, pleural, or pericardial effusion, lung contusion, and thoracotomy.
- Hepatic dysfunction.
- history or new detection of paralysis (no movement) or paradoxical movement of a single hemidiaphragm.
- preexisting cervical spinal injury, history of neuromuscular disorders
- Patients with injuries, burns, or wounds which precluded the proper application of the device electrodes will be also excluded from the study.
- Mechanical ventilation \< 48 hrs
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- Benha Universitylead
Study Sites (1)
Shawky meselhi shawky
Cairo, Egypt
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Doctor
Study Record Dates
First Submitted
July 9, 2023
First Posted
July 17, 2023
Study Start
May 20, 2023
Primary Completion
March 20, 2024
Study Completion
April 20, 2024
Last Updated
July 17, 2023
Record last verified: 2023-07
Data Sharing
- IPD Sharing
- Will not share