NCT05947630

Brief Summary

This study will investigate whether 3D printing of orthoses (night splints and AFO/KAFO for walking, further named as dynamic AFO/KAFO) for the lower limbs can help to improve the limited accessibility to orthopaedic devices in developing countries. The 3D printed orthoses will be assessed for effectiveness, cost and feasibility. Measurement and manufacture of the orthoses is also supported remotely via video conferencing.

Trial Health

90
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
79

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started May 2018

Geographic Reach
3 countries

4 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 15, 2018

Completed
6 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

October 31, 2018

Completed
6 months until next milestone

Study Completion

Last participant's last visit for all outcomes

April 15, 2019

Completed
2.5 years until next milestone

First Submitted

Initial submission to the registry

October 7, 2021

Completed
1.8 years until next milestone

First Posted

Study publicly available on registry

July 17, 2023

Completed
Last Updated

July 17, 2023

Status Verified

July 1, 2023

Enrollment Period

6 months

First QC Date

October 7, 2021

Last Update Submit

July 7, 2023

Conditions

Keywords

lower limb

Outcome Measures

Primary Outcomes (3)

  • 10 meter walk test

    10 meter walk test

    5 weeks

  • knee angle test

    Knee angle test

    5 weeks

  • Ankle angle test

    Ankle angle test

    5 weeks

Secondary Outcomes (2)

  • OPUS questionnnaire

    5 weeks

  • Range of motion

    5 weeks

Study Arms (4)

AFO (ankle foot orthosis) dynamic and correctional

EXPERIMENTAL

Groep A with AFO (ankle foot orthosis) dynamic and correctional

Device: Ankle Foot Orthosis (AFO)

AFO or KAFO (knee ankle foot orthosis) correctional

NO INTERVENTION

Groep B with AFO or KAFO (knee ankle foot orthosis) and only correctional

KAFO dynamic and correctional

EXPERIMENTAL

Groep C with KAFO dynamic and correctional

Device: Knee Ankle Foot Orthosis (KAFO)

KAFO correctional

NO INTERVENTION

Groep D with KAFO only correctional

Interventions

3D treatment (AFO will be printed) versus traditional made AFO

AFO (ankle foot orthosis) dynamic and correctional

3D treatment (KAFO will be printed) versus traditional made KAFO

KAFO dynamic and correctional

Eligibility Criteria

Age4 Years+
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

  • Pathology: foot stance abnormality
  • Both unilateral and bilateral orthoses are included
  • Pathology: genu varum

You may not qualify if:

  • Patient is already wearing a night splint
  • The patient cannot stand upright
  • The patient is pregnant

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (4)

CNAOM

Bamako, Mali

Location

Centre Hospitalier Universitaire de Niamey

Niamey, Niger

Location

CRAO

Dapaong, Togo

Location

CNAO

Lomé, Togo

Location

Related Publications (1)

  • Creylman V, Knippels I, Janssen P, Biesbrouck E, Lechler K, Peeraer L. Assessment of transfemoral amputees using a passive microprocessor-controlled knee versus an active powered microprocessor-controlled knee for level walking. Biomed Eng Online. 2016 Dec 19;15(Suppl 3):142. doi: 10.1186/s12938-016-0287-6.

    PMID: 28105945BACKGROUND

MeSH Terms

Conditions

Musculoskeletal Diseases

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
CROSSOVER
Sponsor Type
OTHER
Responsible Party
SPONSOR INVESTIGATOR
PI Title
Innovation Manager

Study Record Dates

First Submitted

October 7, 2021

First Posted

July 17, 2023

Study Start

May 15, 2018

Primary Completion

October 31, 2018

Study Completion

April 15, 2019

Last Updated

July 17, 2023

Record last verified: 2023-07

Data Sharing

IPD Sharing
Will not share

Locations