Ventilatory Variables in Subjects With Acute Respiratory Distress Syndrome Due to COVID-19
1 other identifier
observational
110
1 country
1
Brief Summary
Research question: Are the ventilatory variables related to mechanical power associated with the outcome of subjects who received mechanical ventilation (MV) for Acute Respiratory Distress Syndrome (ARDS) secondary to pneumonia (NMN) due to COVID-19?
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for all trials
Started Feb 2023
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
Study Start
First participant enrolled
February 10, 2023
CompletedPrimary Completion
Last participant's last visit for primary outcome
February 10, 2023
CompletedStudy Completion
Last participant's last visit for all outcomes
February 10, 2023
CompletedFirst Submitted
Initial submission to the registry
July 10, 2023
CompletedFirst Posted
Study publicly available on registry
July 14, 2023
CompletedJuly 14, 2023
July 1, 2023
Same day
July 10, 2023
July 13, 2023
Conditions
Outcome Measures
Primary Outcomes (7)
global mechanical power
0,098 × Tidal Volume × Respiratory Rate × (Peak Pressure - ½ Driving Pressure)
april 2020 to august 2021
Elastic Dynamic mechanical power
0,098 × Tidal Volume × Respiratory Rate × 0,5 × Driving Pressure
april 2020 to august 2021
Elastic static mechanical power
0,098 × Tidal Volume × Respiratory Rate × PEEP
april 2020 to august 2021
Resistive mechanical power
0,098 × Tidal Volume × Respiratory Rate × (Peak Pressure - Plateau Pressure)
april 2020 to august 2021
Ciclic Strain
Driving Pressure x 4 + Respiratory Rate
april 2020 to august 2021
Death
Death in intensive care unit
april 2020 to august 2021
Suvival
discharge alive from intensive care unit
april 2020 to august 2021
Secondary Outcomes (2)
ventilatory rate
april 2020 to august 2021
PaO2/FiO2
april 2020 to august 2021
Other Outcomes (4)
age
april 2020 to august 2021
sex
april 2020 to august 2021
acute respiratory distress syndrome grade
april 2020 to august 2021
- +1 more other outcomes
Eligibility Criteria
Patients admited to the intensive care unit with Mechanical ventilation due to ARDS with confirmed diagnosis of COVID-19 pneumonia by polymerase chain reaction (PCR),
You may qualify if:
- Confirmed diagnosis of pneumonia due to COVID-19.
- Need of mechanical ventilation in intensive care unit.
You may not qualify if:
- Patients with data loses
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
Hospital Santojanni
Buenos Aires, Argentina
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- RETROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Licenciado Kinesiólogo Fisiatra
Study Record Dates
First Submitted
July 10, 2023
First Posted
July 14, 2023
Study Start
February 10, 2023
Primary Completion
February 10, 2023
Study Completion
February 10, 2023
Last Updated
July 14, 2023
Record last verified: 2023-07