Sleeping Habits on Performance Following Sleep Deprivation

NCT05942664 | Completed

• 1 other identifier: 23-01-019
• Study Type: interventional
• Target: 22
• Locations: 1 country
• Sites: 1

Brief Summary

The goal of this randomized crossover clinical trial is to determine if habitual sleeping habits can predict endurance performance following a night of partial sleep deprivation in healthy untrained, recreationally trained, and trained cyclists (18-50 years, \~50% females). The main questions it aims to answer are:

• Participants will be asked to perform 4 performance tests (20-minute time trial), 2 for familiarization, and 2 testing visits (1 under normal sleep and 1 under partial sleep deprivation).
• For 1 week prior to each testing visit, sleep will be tracked using an ActiGraph device. The investigators hypothesize that habitual early sleepers, poor sleepers, those with greater variability in sleep duration, and females will show the greatest impairments in performance following partial sleep deprivation.

Conditions

Sleep; Athletic Performance; Hemodynamics

Keywords

Sleep habits; Chronotype; Sleep quality; Cycling time trial performance

Outcome Measures

Primary Outcomes (1)

• Performance

  Mean power achieved during a 20-minute time trial on a cycle ergometer

  During each familiarization visit and testing visit (4 time points total)

Other Outcomes (11)

• Resting systolic and diastolic blood pressure

  During both testing visits (2 time points total)

• Resting heart rate

  During both testing visits (2 time points total)

• Systolic and diastolic blood pressure during exercise

  During the introductory visit and during each familiarization visit and testing visit (5 time points total)

Study Arms (2)

Normal sleep

SHAM COMPARATOR

Participants will be asked to sleep during their normal sleep times prior to this visit

Behavioral: Sleep

Sleep deprivation

ACTIVE COMPARATOR

Participants will be asked to go to bed normally but wake up earlier, such that normal sleep duration is restricted by 60%. For example, if someone normally sleeps for 8 hours by falling asleep at 11 pm and waking up at 7 am, they will be asked to fall asleep normally (11 pm) and sleep for 3.2 hours, which results in a wake-up time of 2:12 am.

Behavioral: Sleep

Interventions

Sleep BEHAVIORAL

Sleep will be restricted to 60% normal sleep duration

Normal sleep; Sleep deprivation

Eligibility Criteria

• Age: 18 Years - 50 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64)

You may qualify if:

• Ages 18-50 years
• Free of known cardiovascular or metabolic diseases or sleep disorders
• No history of smoking (within the past 3 months)
• Able to engage in physical activity assessed through the physical activity readiness questionnaire (PAR-Q+) (answer no to all questions
• No prescription of chronic medications other than oral contraceptives
• Able to abide by sleep protocols for all visits
• Individuals who are able to consume the ingredients of instant oatmeal (whole grain oats, sugar, salt, and natural flavour)
• Individuals who are not pregnant

You may not qualify if:

• Ages \<18 years, \>50
• Individuals diagnosed with cardiovascular or metabolic disease or sleep disorders
• Has a history of smoking (within the past 3 months)
• Not ready to engage in physical activity (answer yes to one or more questions in PAR-Q+)
• Individuals with prescription of chronic medications other than oral contraceptives
• Unable to abide by sleep protocols for any testing visit
• Individuals who are unable to consume the ingredients of instant oatmeal (whole grain oats, sugar, salt, and natural flavour)
• Pregnancy

Sponsors & Collaborators

• University of Guelph: lead

Study Sites (1)

University of Guelph - Human Cardiovascular Physiology Laboratory

Guelph, Ontario, N1G2W1, Canada

Location

MeSH Terms

Conditions

Sleep Initiation and Maintenance Disorders

Interventions

Sleep

Condition Hierarchy (Ancestors)

Sleep Disorders, Intrinsic; Dyssomnias; Sleep Wake Disorders; Nervous System Diseases; Mental Disorders

Intervention Hierarchy (Ancestors)

Nervous System Physiological Phenomena; Musculoskeletal and Neural Physiological Phenomena

Study Officials

• Philip Millar

  University of Guelph

  PRINCIPAL INVESTIGATOR

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, INVESTIGATOR
• Masking Details: Participants and investigators are blinded to power output during the time trial
• Purpose: DIAGNOSTIC
• Intervention Model: CROSSOVER
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Associate Professor

Study Record Dates

• First Submitted: June 26, 2023
• First Posted: July 12, 2023
• Study Start: June 26, 2023
• Primary Completion: May 5, 2024
• Study Completion: May 6, 2024
• Last Updated: December 6, 2024

Record last verified: 2024-12

Locations

CA (1)