Young Adult-Mediated Intervention to Increase Colorectal Cancer Screening

NCT05936931 | Not Yet Recruiting DMC

• 3 other identifiers: IRB202300089R03CA270837-01A1HM20026698
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

This study will garner preliminary data to develop a young adult-mediated intervention whereby a younger family member encourages their older family member to get colorectal cancer (CRC) screening. In Aim 1, survey data from n=150 younger (25-44 years old) and n=150 older (45-75 years old) adults living in rural communities will be collected. In Aim 2, intervention components will be evaluated using n=9 focus groups. The novel intervention will be assessed via a pilot trial (n=15 adult child/parent dyads) in Aim 3.

Conditions

Young Adult-Mediated Intervention to Increase Colorectal Cancer Screening

Outcome Measures

Primary Outcomes (2)

• CRC screening knowledge and awareness

  A composite index score on four awareness items and 14 knowledge items adopted from prior research

  2-months post-intervention

• CRC screeningintentions

  A single item, based on previous CRC screening research

  2-months post-intervention

Study Arms (1)

Aim 3: Single arm, open-label, pre-test/post-test design pilot trial

OTHER

Single arm, open-label, pre-test/post-test design pilot trial

Behavioral: Changes in CRC screening awareness and intentions

Interventions

Changes in CRC screening awareness and intentions BEHAVIORAL

Using a single arm, open-label, pre-test post-test design (n=15 adult child/parent dyads), assess the impact of a young adult-mediated intervention to increase CRC screening among a paired age-eligible family member (e.g., parent/grandparent). The focus of the intervention will be on changes in CRC screening awareness and intentions among the age-eligible adult, but we hypothesize that the young adult could benefit as well. Thus, in addition to assessing feasibility and acceptability, we will assess changes in 1) CRC screening intentions among the age-eligible adults and 2) CRC health literacy and awareness of screening guidelines among the younger adult participant.

Aim 3: Single arm, open-label, pre-test/post-test design pilot trial

Eligibility Criteria

• Age: 25 Years - 75 Years
• Sex: all
• Healthy Volunteers: Yes
• Age Groups: Adult (18-64), Older Adult (65+)

You may qualify if:

• Residents of counties in the Virginia/North Carolina CRC hotspot
• years old
• Able to speak, write, and comprehend English
• Younger adult participants in Aims 3 must have an older, screening age-eligible relative with whom they speak with regularly (i.e., ≥ once every two weeks)

You may not qualify if:

• Participants in Aims 1 or 2 will be ineligible for Aim 3

Sponsors & Collaborators

• Virginia Commonwealth University: lead
• National Cancer Institute (NCI): collaborator

Study Sites (1)

Virginia Commonwealth University

Richmond, Virginia, 23289, United States

Location

Study Officials

• Carrie A Miller, PhD, MPH

  Virginia Commonwealth University

  PRINCIPAL INVESTIGATOR

Central Study Contacts

Carrie A Miller, PhD, MPH

CONTACT

(804) 628-8188; carrie.a.miller@vcuhealth.org

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NA
• Masking: NONE
• Purpose: SCREENING
• Intervention Model: SINGLE GROUP
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: June 23, 2023
• First Posted: July 10, 2023
• Study Start (Estimated): July 31, 2026
• Primary Completion (Estimated): December 31, 2027
• Study Completion (Estimated): December 31, 2027
• Last Updated: April 15, 2026

Record last verified: 2026-04

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)