Acupuncture Therapy VS Chiropractor Group Therapy to Reduce Anxiety and Depression.

NCT05936905 | Completed

• 1 other identifier: YSU8232022
• Study Type: interventional
• Target: 30
• Locations: 1 country
• Sites: 1

Brief Summary

This study aims to determine and compare acupuncture therapy and chiropractor group therapy to reduce anxiety and depression among HIV/AIDS patients at Being Alive, Los Angeles. In this controlled clinical trial, a total of 30 patients will be divided into two groups, 15 in the acupuncture therapy group, 15 in the chiropractor group therapy. The Hospital Anxiety and Depression Scale (HADS), The Patient Health Questionnaire 9-item (PHQ-9) and Generalized Anxiety Disorder 7- item scales (GAD-7) will be used as screening tools for depressive and anxiety symptoms respectively.

Conditions

Anxiety Depression; HIV/AIDS

Keywords

Anxiety and depression; People living with HIV/AIDS (PLWH/A); Acupuncture; Chiropractor

Outcome Measures

Primary Outcomes (3)

• Hospital Anxiety and Depression Scale (HADS)

  Seven item questionnaire of each anxiety and depression. The items are rated on 0, 1, 2, and 3 giving scores with minimum scores of 0 to 21 maximum. Score interpretation on anxiety or depression subscales ranging from 0-7 considered non case, 8-10 considered possible case, and 11-21 considered probable case, which have been reclassified and relabeled as follows: 0-7 normal, 8-10 = mild, 11-15= moderate, and ≥16 = severe of anxiety or depression.

  3 months

• The Patient Health Questionnaire 9-item (PHQ-9)

  Patient Health Questionnaire for depression, score interpretation. Severity. The developers report the following interpretive guidelines for the PHQ-9 as a severity measure: 1-4 no depression, 5-9 = mild de- pression, 10-14= moderate depression, 15-19 = moderately severe depression, and 20-27= severe depression.

  3 months

• Generalized Anxiety Disorder 7-item (GAD-7)

  Anxiety Disorder 7-item, scoring Scores of 5, 10, and 15 are taken as the cut-off points for mild, moderate, and severe anxiety, respectively.

  3 months

Study Arms (2)

Acupuncture therapy

EXPERIMENTAL

This study aims to compare acupuncture therapy administered one time per month

Other: Acupuncture

Chiropractor therapy

EXPERIMENTAL

This study aims to compare chiropractic therapy administered one time per month

Other: Chiropractic

Interventions

Acupuncture OTHER

Acupuncture 1 time per month

Acupuncture therapy

Chiropractic OTHER

Chiropractic 1 time per month

Chiropractor therapy

Eligibility Criteria

• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)

You may qualify if:

• single intervention only

You may not qualify if:

• chiropractic and acupuncture together

Sponsors & Collaborators

• Yo San University of Traditional Chinese Medicine: lead

Study Sites (1)

Yo San University

Los Angeles, California, 90066, United States

Location

MeSH Terms

Conditions

Acquired Immunodeficiency Syndrome; Anxiety Disorders; Depression

Interventions

Acupuncture Therapy; Manipulation, Chiropractic

Condition Hierarchy (Ancestors)

HIV Infections; Blood-Borne Infections; Communicable Diseases; Infections; Sexually Transmitted Diseases, Viral; Sexually Transmitted Diseases; Lentivirus Infections; Retroviridae Infections; RNA Virus Infections; Virus Diseases; Slow Virus Diseases; Genital Diseases; Urogenital Diseases; Immunologic Deficiency Syndromes; Immune System Diseases; Mental Disorders; Behavioral Symptoms; Behavior

Intervention Hierarchy (Ancestors)

Complementary Therapies; Therapeutics; Musculoskeletal Manipulations

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: NON RANDOMIZED
• Masking: DOUBLE
• Who Masked: CARE PROVIDER, INVESTIGATOR
• Masking Details: Single blind non randomized clinical trial.
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: CEO/DEAN

Model Details: Staff members will administer the HADS, PHQ-9 and GAD-7 through a questionnaire. The scale is being administered to a convenience sample of 30 HIV/AIDs patients, divided into 15 samples of acupuncture treatment and 15 samples of chiropractor treatment, duration 3 months. Patients will complete questionnaire before and at the end of the treatments. Data to be collected includes socio-demographic. Symptoms of anxiety and depression are measured using the Hospital Anxiety and Depression Scale (HADS). The items are rated on 0, 1, 2, and 3 giving scores with minimum scores of 0 to 21. Scores on anxiety or depression subscales ranging from 0-7 are considered normal; 8-10 are considered cause for concern, borderline abnormal, and 11-21 are considered abnormal probable cases of anxiety or depression. The Patient Health Questionnaire 9-item(PHQ-9) if (score ≥9) significant mild depressive symptom and Generalized Anxiety Disorder 7-item (GAD-7) scale, if (score 8+) probable anxiety disorder.

Study Record Dates

• First Submitted: June 22, 2023
• First Posted: July 10, 2023
• Study Start: December 6, 2022
• Primary Completion: March 1, 2024
• Study Completion: August 1, 2024
• Last Updated: July 14, 2025

Record last verified: 2025-07

Data Sharing

• IPD Sharing: Will not share

Locations

US (1)