NCT05932875

Brief Summary

The primary objective of this proposal is to determine the effects of post-exercise peanut consumption on long-term aerobic and resistance exercise training adaptations in middle-aged men and women. The investigators will determine the impact of peanuts on exercise training-induced improvements in muscle strength, gains in muscle mass, and improvements in cardiorespiratory fitness and metabolic capacity.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
34

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started May 2023

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 30, 2023

Completed
28 days until next milestone

First Submitted

Initial submission to the registry

June 27, 2023

Completed
9 days until next milestone

First Posted

Study publicly available on registry

July 6, 2023

Completed
12 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 15, 2024

Completed
16 days until next milestone

Study Completion

Last participant's last visit for all outcomes

July 1, 2024

Completed
Last Updated

April 24, 2025

Status Verified

April 1, 2025

Enrollment Period

1 year

First QC Date

June 27, 2023

Last Update Submit

April 21, 2025

Conditions

Keywords

peanutmuscle healthconcurrent trainingcardiorespiratory fitness

Outcome Measures

Primary Outcomes (3)

  • Total Lean Mass

    Amount of lean mass as determined by dual energy x-ray absorptiometry scan

    From baseline to the end of the training program at 16 weeks.

  • Muscle strength

    Isometric grip and knee extension strength, as well as dynamic 1-repitition maximum strength of bench press, leg press, overhead press, knee extension

    From baseline to the end of the training program at 16 weeks.

  • Cardiorespiratory fitness

    Maximal oxygen consumption as determined by graded treadmill test

    From baseline to the end of the training program at 16 weeks.

Study Arms (2)

Peanut/Carbohydrate Consumption Exercise Training

ACTIVE COMPARATOR

Participants in this group will undergo 16 weeks of concurrent exercise training (4 sessions/week) consuming a peanut-based rice/oatmilk smoothie after each workout

Other: Exercise Training

Carbohydrate Consumption Exercise Training

PLACEBO COMPARATOR

Participants in this group will undergo 16 weeks of concurrent exercise training (4 sessions/week) consuming a rice/oatmilk smoothie after each workout

Other: Exercise Training

Interventions

4 day per week concurrent exercise training program

Carbohydrate Consumption Exercise TrainingPeanut/Carbohydrate Consumption Exercise Training

Eligibility Criteria

Age30 Years - 55 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64)

You may qualify if:

  • Men and women 30- 55 years old
  • healthy
  • non-smoking
  • no exercise training in the previous 6 months
  • not currently attempting to gain or lose weight
  • body mass index \< 35
  • no need for physician clearance prior to beginning an exercise program as determined by American College of Sports Medicine guidelines.

You may not qualify if:

  • neurological or musculoskeletal disorders
  • uncontrolled hypertension (resting systolic blood pressure \> 180 mmHg or diastolic \> 120 mmHg
  • unstable or exercise-induced angina pectoris
  • diabetes mellitus; any other medical condition that would interfere with testing or training
  • androgen (e.g., testosterone), anabolic (e.g., GH, IGF-I), or catabolic (e.g. GLP-1 agonists) therapy
  • food allergy to peanuts or dairy products
  • pregnant people or people actively trying to get pregnant
  • on a special diet that restricts protein/carbs/sugar/fat.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Southwestern University

Georgetown, Texas, 78626, United States

Location

MeSH Terms

Interventions

Exercise

Intervention Hierarchy (Ancestors)

Motor ActivityMovementMusculoskeletal Physiological PhenomenaMusculoskeletal and Neural Physiological Phenomena

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
PARTICIPANT
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Associate Professor of Kinesiology

Study Record Dates

First Submitted

June 27, 2023

First Posted

July 6, 2023

Study Start

May 30, 2023

Primary Completion

June 15, 2024

Study Completion

July 1, 2024

Last Updated

April 24, 2025

Record last verified: 2025-04

Data Sharing

IPD Sharing
Will not share

IRB approval does not allow for IPD to be shared.

Locations