NCT05927532

Brief Summary

The purpose of the investigation is to confirm the safety and performance of the Argyle™ Safety Fistula Cannula with Anti-reflux Valve for hemodialysis treatment.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
40

participants targeted

Target at P25-P50 for not_applicable

Timeline
Completed

Started Mar 2024

Shorter than P25 for not_applicable

Geographic Reach
1 country

3 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

January 19, 2023

Completed
6 months until next milestone

First Posted

Study publicly available on registry

July 3, 2023

Completed
8 months until next milestone

Study Start

First participant enrolled

March 10, 2024

Completed
9 months until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 15, 2024

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 15, 2024

Completed
Last Updated

March 17, 2026

Status Verified

March 1, 2026

Enrollment Period

9 months

First QC Date

January 19, 2023

Last Update Submit

March 13, 2026

Conditions

Outcome Measures

Primary Outcomes (1)

  • Successful Hemodialysis Sessions

    The primary objective is the percentage of successful hemodialysis sessions using the Argyle™ Safety Fistula Cannula with Anti-reflux Valve.

    through study completion, an average of 1 year

Secondary Outcomes (8)

  • Successful Cannulations

    through study completion, an average of 1 year

  • Cannulation Locations with securement details

    through study completion, an average of 1 year

  • Access-related complications requiring procedural intervention

    through study completion, an average of 1 year

  • Compare prescribed blood flow rates

    through study completion, an average of 1 year

  • Dialysis adequacy

    through study completion, an average of 1 year

  • +3 more secondary outcomes

Other Outcomes (2)

  • Summary of Needle Stick Injury within past 6 months from start of study by investigational site

    in the past 6 months from the start of the study

  • Time to successful cannulation

    During procedure

Study Arms (1)

Argyle Fistula Cannula Subjects

EXPERIMENTAL

All subjects enrolled in the study and treated with the Argyle Safety Fistula Cannula with Anti-reflux Valve

Device: Argyle Safety Fistula Cannula with Anti-Reflux Valve

Interventions

The Argyle Safety Fistula Cannula with Anti-reflux Valve will be used 3x a week for 12 weeks in subjects with an arteriovenous fistulae (AVF) fistula

Argyle Fistula Cannula Subjects

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Subject who is aged 18 years or older who signed informed consent
  • Subject is undergoing in-center hemodialysis
  • Subject has an arteriovenous fistulae (AVF) fistula that was determined to be mature by standard clinical definition

You may not qualify if:

  • Subject is enrolled in another study that could confound the results of this study, without documented pre-approval
  • Subject with an existing arteriovenous graft
  • Subjects with known allergies to plastics
  • Subjects who are unable to read or respond to the questionnaire about satisfaction

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (3)

DaVita Hartford

Hartford, Connecticut, 06082, United States

Location

DaVita Columbus

Columbus, Georgia, 31904, United States

Location

DaVita Norfolk

Norfolk, Virginia, 23505, United States

Location

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

January 19, 2023

First Posted

July 3, 2023

Study Start

March 10, 2024

Primary Completion

December 15, 2024

Study Completion

December 15, 2024

Last Updated

March 17, 2026

Record last verified: 2026-03

Data Sharing

IPD Sharing
Will not share

Locations