Acute Phase Reactant in Non-COVID-19 Bacterial Pneumonia

NCT05926089 | Completed

• 1 other identifier: MS-358-2020
• Study Type: observational
• Target: 51
• Locations: 1 country
• Sites: 1

Brief Summary

This study is a cross-sectional study, was conducted at Chest department of Kasr Al-ainy Hospital, Cairo university during the period between October 2020 and April 2021. The aim of the work was to evaluate levels of acute phase reactants(APR) in Non-COVID-19 bacterial pneumonia, and to correlate between levels of APR and the disease severity.

Conditions

Pneumonia; Acute-Phase Reaction

Outcome Measures

Primary Outcomes (1)

• measurement of APR levels in non-Covid-19 pneumonia

  assessment of the level of APR and its relation to disease severity

  6 months

Interventions

Blood sampling DIAGNOSTIC_TEST

blood sampling to measure APR

Eligibility Criteria

• Age: 18 Years - 75 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Probability Sample

Study Population

All patients( 51 patients diagnosed as non-COVID19 Pneumonia) were subjected to: 1. Full historywith emphasis on: * Epidemiological features . * Risk factors (smoking, DM). * Clinical presentation (cough, Fever and duration of ilness). 2. Clinical examination (local chest examination). 3. Laboratory investigations: venous blood samples were taken for:• Complete blood picture, differential leucocytic count and platelets count, ESR ,CRP, d-dimer and ferritin

You may qualify if:

• COVID-19 negative bacterial pneumonia

You may not qualify if:

• COVID-19 positive
• other non-pulmonary infections

Sponsors & Collaborators

• Cairo University: lead

Study Sites (1)

Kasr alainy school of medicine

Cairo, 11562, Egypt

Location

Biospecimen

Retention: SAMPLES WITHOUT DNA

• Complete blood picture, differential leucocytic count and platelets count: Done by The newly developed automated hematology analyzer (Sysmex, Kobe, Japan) enumerates and classifies blood cells by a combination of direct current detection and flow cytometry. (Daves et al., 2015).

MeSH Terms

Conditions

Pneumonia; Acute-Phase Reaction

Interventions

Blood Specimen Collection

Condition Hierarchy (Ancestors)

Respiratory Tract Infections; Infections; Lung Diseases; Respiratory Tract Diseases; Inflammation; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

Specimen Handling; Clinical Laboratory Techniques; Diagnostic Techniques and Procedures; Diagnosis; Punctures; Surgical Procedures, Operative; Investigative Techniques

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Assistant Professor of pulmonology

Study Record Dates

• First Submitted: June 28, 2023
• First Posted: July 3, 2023
• Study Start: October 1, 2020
• Primary Completion: April 30, 2021
• Study Completion: May 30, 2021
• Last Updated: July 14, 2023

Record last verified: 2023-07

Data Sharing

• IPD Sharing: Will not share

Locations

EG (1)