Effect of Fermented Products and Probiotics on the Condition of the Implant

NCT05921357 | Completed

• 1 other identifier: 2022/196
• Study Type: observational
• Target: 126
• Locations: 1 country
• Sites: 1

Brief Summary

126 individuals with peri-implant disease and health, aged between 18-70 years, who applied to Bolu University Faculty of Dentistry Periodontology Clinic, participated in the study.The inclusion criteria for patient participation in the study were: age of patients between 18 and 70 years; the presence of at least 20 natural teeth in the oral cavity; systemic health. Peri-implant status was determined by the clinician (T.Ş.) by evaluating dental implants' plaque, gingival index, bleeding on probing, pocket depth measurements, and clinical attachment level. In addition, them systemic illness, pregnancy, breastfeeding status, medication, antibiotic use, and whether they smoked were questioned. Systemically unhealthy patients who did not use antibiotics within a month, were breastfeeding or pregnant, had uncontrolled diabetes, rheumatic fever, a history of lung and kidney disorders, and used drugs that could affect periodontal tissues were not included in the study. After examination, the patients were divided into three groups according to their disease: Peri-implantitis (42 patients), peri-implantitis (42 patients), and peri-implant health (42 patients). Demographic characteristics (age, weight, gender, height, education, and employment status) of the participants were collected with a questionnaire. With this survey, fermented foods and probiotic products such as bacon, soy sauce, pickles, sourdough bread, whole grain, rye, wholemeal bread, ayran, kefir, turnip, vinegar (homemade), pomegranate syrup (homemade), probiotic beverage, the frequency and amount of consumption of cheese, dark chocolate, tablets, capsules, chassis, butter and other (Kimchi, sauerkrauth, miso soup, fermented herring, kombucha, etc.) were determined. It was requested to determine the relationship between the health and disease of the implant and the frequency of consumption of fermented and probiotic products and foods in individuals with implants.

Conditions

Implant

Keywords

Fermented foods; probiotics; peri-implant health; peri-implant mucositis; peri-implantitis

Outcome Measures

Primary Outcomes (5)

• Consumption frequency

  the number of times a product is consumed in a given time period.

  Baseline

• Consumption amount

  The average quantity of an item consumed or expended during a given time interval, expressed in quantities by the most appropriate unit of measurement per applicable stated basis.

  Baseline

• Daily intake

  The amount of a substance that people can consume on a daily basis

  Baseline

• Bleeding on probing

  Bleeding, leading sign of inflammation inside the connective tissue, is a critical factor for pocket depth measurements, and with other variable factors prevents making reproducible measurements.

  Baseline

• Periodontal pocket depth

  a pathologically deepened gingival sulcus around a tooth at the gingival margin.

  Baseline

Secondary Outcomes (3)

• Plaque index

  Baseline

• Gingival index

  Baseline

• Clinical attachment level

  Baseline

Study Arms (3)

Peri-implantitis

Implants with a pocket depth of more than 5 mm and bleeding on probing

Other: Questionnaire

Peri-implant mucositis

Implants with no bone loss but bleeding on probing

Other: Questionnaire

Peri-implant health

Implants with no bone loss but no bleeding on probing

Other: Questionnaire

Interventions

Questionnaire OTHER

Questionnaire and examine

Peri-implant health; Peri-implant mucositis; Peri-implantitis

Eligibility Criteria

• Age: 18 Years - 70 Years
• Sex: female
• Healthy Volunteers: No
• Age Groups: Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

Bolu Abant İzzet Baysal University

You may qualify if:

• Systemically healthy individuals
• Individuals between the ages of 18-70

You may not qualify if:

• No use of antibiotics within one month
• Breastfeeding or being pregnant
• Uncontrolled diabetes, rheumatic fever, history of lung and kidney disorders, and drug use that will affect periodontal tissues

Sponsors & Collaborators

• Tuğba ŞAHİN: lead

Study Sites (1)

Bolu Abant İzzet Baysal University

Bolu, Turkey, Turkey (Türkiye)

Location

MeSH Terms

Conditions

Peri-Implantitis

Interventions

Surveys and Questionnaires

Condition Hierarchy (Ancestors)

Periodontal Diseases; Mouth Diseases; Stomatognathic Diseases

Intervention Hierarchy (Ancestors)

Data Collection; Epidemiologic Methods; Investigative Techniques; Health Care Evaluation Mechanisms; Quality of Health Care; Health Care Quality, Access, and Evaluation; Public Health; Environment and Public Health

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: CROSS SECTIONAL
• Sponsor Type: OTHER
• Responsible Party: SPONSOR INVESTIGATOR
• PI Title: Assistant professor

Study Record Dates

• First Submitted: June 18, 2023
• First Posted: June 27, 2023
• Study Start: July 4, 2022
• Primary Completion: July 4, 2022
• Study Completion: March 31, 2023
• Last Updated: February 4, 2025

Record last verified: 2025-02

Locations

TU (1)