NCT05917691

Brief Summary

The goal of this observational study is to assess the effect of functional status on bariatric surgical thirty-day outcomes. The main questions it aims to answer are:

  • Is functional status associated with higher incidence of 30-day unplanned resource utilization?
  • Is functional status associated with higher incidences of secondary adverse events? Participants will be sampled from the 2015-2019 American College of Surgeons National Surgical Quality Improvement Program

Trial Health

100
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
65,627

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jan 2015

Longer than P75 for all trials

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 1, 2015

Completed
5 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 31, 2019

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 31, 2019

Completed
3.4 years until next milestone

First Submitted

Initial submission to the registry

June 5, 2023

Completed
21 days until next milestone

First Posted

Study publicly available on registry

June 26, 2023

Completed
Last Updated

June 26, 2023

Status Verified

June 1, 2023

Enrollment Period

5 years

First QC Date

June 5, 2023

Last Update Submit

June 23, 2023

Conditions

Outcome Measures

Primary Outcomes (1)

  • Unplanned resource utilization (composite)

    A composite binary outcome comprising unplanned readmission, return to the operating room, or prolonged (≥ 30 day) length of stay.

    30 days

Secondary Outcomes (2)

  • Composite organ system complications

    30 days

  • Mortality

    30 days

Study Arms (2)

Dependent functional status

223 patients; "dependent" for those documented as "partially dependent" or "totally dependent."

Procedure: Bariatric surgeryDrug: General anestheticDevice: Indeterminate

Independent functional status

65404 patients; "independent" for those documented as such.

Procedure: Bariatric surgeryDrug: General anestheticDevice: Indeterminate

Interventions

Current Procedural Terminology (CPT) codes: 43644, 43645, 43770, 43775, 43842, 43843, 43845, 43846, 43847.

Dependent functional statusIndependent functional status

Cases were required to have a documented "general anesthesia" anesthetic technique. Administered drugs were otherwise indeterminate under the current study design (observational study of a deidentified database).

Dependent functional statusIndependent functional status

Devices were indeterminate under the current study design (observational study of a deidentified database).

Dependent functional statusIndependent functional status

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Elective bariatric surgical patients, ACS-NSQIP 2015-2019

You may qualify if:

  • Current Procedural Terminology (CPT) codes: 43644, 43645, 43770, 43775, 43842, 43843, 43845, 43846, 43847
  • Elective, non-emergent cases
  • "General surgery" surgical specialty
  • "General anesthesia" anesthetic technique

You may not qualify if:

  • Documented concurrent or other procedures
  • Patients admitted to the hospital for greater than one day preceding surgery
  • Acute kidney injury (preoperative)
  • End-stage renal disease (preoperative)
  • Metastatic disease (preoperative)
  • Wound infection (preoperative)
  • Sepsis (preoperative)

Contact the study team to confirm eligibility.

Sponsors & Collaborators

MeSH Terms

Conditions

Postoperative ComplicationsFrailty

Interventions

Bariatric SurgeryAnesthetics, General

Condition Hierarchy (Ancestors)

Pathologic ProcessesPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

BariatricsObesity ManagementTherapeuticsSurgical Procedures, OperativeAnestheticsCentral Nervous System DepressantsPhysiological Effects of DrugsPharmacologic ActionsChemical Actions and UsesCentral Nervous System AgentsTherapeutic Uses

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
Principal Investigator

Study Record Dates

First Submitted

June 5, 2023

First Posted

June 26, 2023

Study Start

January 1, 2015

Primary Completion

December 31, 2019

Study Completion

December 31, 2019

Last Updated

June 26, 2023

Record last verified: 2023-06

Data Sharing

IPD Sharing
Will share

American College of Surgeons National Surgical Quality Improvement Program and the hospitals participating in the ACS NSQIP are the source of the data used herein. The Participant Use Data File (PUF) is a Health Insurance Portability and Accountability Act (HIPAA)-compliant data file containing cases submitted to the American College of Surgeons National Surgical Quality Improvement Program®. To request a copy of the PUF, individuals (data recipients) must agree to comply with the terms and conditions set forth in the Data Use Agreement, provide contact information, and complete a short online questionnaire. Once the information provided by the data recipient is received and processed by ACS NSQIP staff, a website address will be submitted electronically to the data recipient. The data recipient will then have 10 days (240 hours) to visit the website and download the data file.

Available IPD Datasets

Individual Participant Data Set Access