Study Stopped
Due to lack of funding, we have been unable to continue research activities. The future related to funding support does not look promising, therefore it is best to discontinue this project.
Comorbid Painful TMD Among Trigeminal Neuralgia
TNTMD
Comorbid Painful Temporomandibular Disorder Among Trigeminal Neuralgia Patients
2 other identifiers
observational
N/A
1 country
2
Brief Summary
An observational study following up with trigeminal neuralgia patients to understand their comorbid facial pain condition, specifically temporomandibular disorder.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
Started Aug 2022
Longer than P75 for all trials
2 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
August 1, 2022
CompletedFirst Submitted
Initial submission to the registry
June 13, 2023
CompletedFirst Posted
Study publicly available on registry
June 22, 2023
CompletedPrimary Completion
Last participant's last visit for primary outcome
August 30, 2026
ExpectedStudy Completion
Last participant's last visit for all outcomes
August 30, 2026
December 31, 2025
December 1, 2025
4.1 years
June 13, 2023
December 23, 2025
Conditions
Outcome Measures
Primary Outcomes (1)
Prevalence
Prevalence of comorbid painful TMD among TN patient
2 years
Secondary Outcomes (1)
Diagnostic questionnaire
2 years
Study Arms (1)
TN cohort
The patient was diagnosed with trigeminal neuralgia which has active symptoms in the past 30 days.
Interventions
One clinical interview and examination to confirm the diagnosis of trigeminal neuralgia and temporomandibular disorder.
Eligibility Criteria
Patients that visited three clinical centers in the study who sought care for their facial pain were diagnosed with trigeminal neuralgia, with active symptoms in the past 30 days.
You may qualify if:
- Patients visited the three clinical sites for facial pain
- Patients diagnosed with trigeminal neuralgia
- Has active pain symptoms in the past 30 days
You may not qualify if:
- Non-English speakers
- Patients with psychiatric disorders that might alter pain perception
- Adults lack the capacity to provide informed consent.
- Persons under the age of 18.
- All vulnerable populations.
Contact the study team to confirm eligibility.
Sponsors & Collaborators
- University of Minnesotalead
- Johns Hopkins Universitycollaborator
Study Sites (2)
John Hopkins University
Baltimore, Maryland, 21287, United States
University of Minnesota, Department of Neurosurgery
Minneapolis, Minnesota, 55455, United States
MeSH Terms
Conditions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Donald Nixdorf, DDS,MS
University of Minnesota
- STUDY DIRECTOR
Qiman Gao, DDS,MS,PhD
University of Minnesota
Study Design
- Study Type
- observational
- Observational Model
- COHORT
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
June 13, 2023
First Posted
June 22, 2023
Study Start
August 1, 2022
Primary Completion (Estimated)
August 30, 2026
Study Completion (Estimated)
August 30, 2026
Last Updated
December 31, 2025
Record last verified: 2025-12
Data Sharing
- IPD Sharing
- Will share
- Shared Documents
- CSR
- Time Frame
- By end of 2024
The final results will be shared with all the participants as a summary.