Impact Of Sensory Re-Education Paradigm On Sensation And Quality Of Life In Patients Post-Covid 19 Polyneuropathy

NCT05911113 | Completed

• 1 other identifier: P.T.REC/012/004416
• Study Type: interventional
• Target: 40
• Locations: 1 country
• Sites: 1

Brief Summary

This study will be conducted to investigate the effect of a sensory re-education paradigm on sensation and proprioception in patients with post covid-19 neuropathy.

Conditions

Post-COVID-19 Syndrome

Keywords

post-covid 19 polyneuropathy; sensory re-education paradigm; sensation; quality of life

Outcome Measures

Primary Outcomes (1)

• disability of life

  disability of life will be measured using the Arabic, validated version of WHOQOL-BREF questionnaire. The scale consists of 26 items; the first two items address an individual's perception of his/her overall quality of life and health, respectively, and the remaining 24 items assess the four quality of life domains; Physical Health (seven items), Psychological (six items), Social Relationships (three items), and Environment (eight items). Each item is rated on a five-point Likert scale. The final scores were converted into a linear scale between 0 and 100 according to the scoring guidelines where higher scores indicate higher disability.

  up to six weeks

Secondary Outcomes (3)

• Tactile sensation

  up to six weeks

• hand grip strength

  up to six weeks

• joint position error

  up to six weeks

Study Arms (2)

sensory re-education training

EXPERIMENTAL

the patients will receive sensory re-education training three times a week for six weeks

Other: sensory re-education training; Other: traditional treatment

traditional treatment

ACTIVE COMPARATOR

the patients will receive traditional treatment three times a week for six weeks

Other: traditional treatment

Interventions

sensory re-education training OTHER

the patients will receive sensory re-education training in the form of texture discrimination training, limb position sense and tactile object recognition

sensory re-education training

traditional treatment OTHER

the Patients in this group will receive traditional treatment in the form of proprioception neuromuscular facilitation (PNF) and graduated active and resisted wrist and hand muscle strengthening exercises.

sensory re-education training; traditional treatment

Eligibility Criteria

• Age: 30 Years - 40 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Adult (18-64)

You may qualify if:

• Patients from both genders (male and female). The age of participants ranged from 30 to 40 years old. Participants were required to live in Egypt during the pre-covid and COVID-19 pandemic.
• Patients with confirmation of previous covid19 infection PCR TEST. Patients meeting the guide line of world health organization (WHO) of long/post-covid 19 syndromes.
• Patients with unknown prior neuropathy. Patients with neuropathy confirmed by EDX with a sensory nerve conduction velocity.

You may not qualify if:

• Patients with Diabetes mellitus (DM), Rheumatology and Guillain-Barré syndrome (GBS).
• Infection other than covid19 leading to sensory neuropathy. Traumatic or compressive lesions leading to central nervous system (CNS), peripheral nervous system (PNS) damages.
• Previous surgeries or medications leading to neuropathy.

Sponsors & Collaborators

• Cairo University: lead

Study Sites (1)

Faculty of Physical Therapy

Cairo, Egypt

Location

MeSH Terms

Conditions

Post-Acute COVID-19 Syndrome

Condition Hierarchy (Ancestors)

COVID-19; Pneumonia, Viral; Pneumonia; Respiratory Tract Infections; Infections; Virus Diseases; Coronavirus Infections; Coronaviridae Infections; Nidovirales Infections; RNA Virus Infections; Lung Diseases; Respiratory Tract Diseases; Post-Infectious Disorders; Chronic Disease; Disease Attributes; Pathologic Processes; Pathological Conditions, Signs and Symptoms

Study Design

• Study Type: interventional
• Phase: not applicable
• Allocation: RANDOMIZED
• Masking: DOUBLE
• Who Masked: PARTICIPANT, OUTCOMES ASSESSOR
• Masking Details: opaque sealed envelope
• Purpose: TREATMENT
• Intervention Model: PARALLEL
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: principle investigator younes ali khadour

Model Details: sensory re-education and traditional therapy

Study Record Dates

• First Submitted: June 17, 2023
• First Posted: June 20, 2023
• Study Start: June 26, 2023
• Primary Completion: August 30, 2023
• Study Completion: October 30, 2023
• Last Updated: February 14, 2024

Record last verified: 2024-02

Locations

EG (1)