NCT05909254

Brief Summary

The first choice therapy in case of palatally impacted canines is their exposure and orthodontic eruption to improve facial esthetics and prevent pathologies associated with impacted teeth and Temporomandibular Joint Disorders. Current solutions in digital dentistry allow the registration of three dimensional imaging datasets such as cone beam computed tomography (CBCT) and digital impression of the dentition and soft tissues obtained via intraoral scanning using orthodontic planning software. This allows the surgeon to visualize the position of the impacted canine prior to surgery and to design and manufacture a surgical guide to aid in the localization of the impacted tooth during surgery. The aim of this randomized clinical trial is to assess the feasibility of surgical exposure of palatally impacted upper canines with open-eruption technique using a surgical template. The secondary purpose of this study is to compare this method with the conventional free-hand surgical exposure. Patients included in this study are randomly assigned to two study groups. In Group 1 surgical exposure for open eruption of palatally impacted canines is performed following virtual planning using a surgical template. In Group 2 surgical exposure for open-eruption of palatally impacted canines is carried out using the conventional free-hand method. We hypothesize that guided exposure of the impacted canines will be as successful as the conventional method with shorter surgical intervention and higher associated costs.

Trial Health

75
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
40

participants targeted

Target at P25-P50 for not_applicable

Timeline
26mo left

Started May 2023

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
active not recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress58%
May 2023Jun 2028

Study Start

First participant enrolled

May 1, 2023

Completed
1 month until next milestone

First Submitted

Initial submission to the registry

May 31, 2023

Completed
18 days until next milestone

First Posted

Study publicly available on registry

June 18, 2023

Completed
4.9 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

April 30, 2028

Expected
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

June 30, 2028

Last Updated

April 22, 2026

Status Verified

April 1, 2026

Enrollment Period

5 years

First QC Date

May 31, 2023

Last Update Submit

April 21, 2026

Conditions

Keywords

surgical exposureopen eruption technique

Outcome Measures

Primary Outcomes (2)

  • Success of the intervention

    Measures if an attachment could be bonded to the impacted tooth during the surgery.

    on the day of the surgery

  • Success of the open eruption technique

    Measures whether the canine erupts in its correct place in the dentition following tha application of orthodontic forces.

    1 year

Secondary Outcomes (4)

  • Surplus costs of surgical planning and manufacturing the surgical guide

    through study completion, an average of 1 years

  • Duration of the surgical intervention

    during surgery

  • Postoperative pain

    1 week

  • Intra- and postoperative complications associated with surgery

    through study completion, an average of 1 years

Study Arms (2)

Palatally impacted canine exposure using a surgical template

EXPERIMENTAL
Other: Palatally impacted canine exposure using a surgical guide

Palatally impacted canine exposure using the conventional free-hand method

EXPERIMENTAL
Other: Palatally impacted canine exposure using the conventional free.hand method

Interventions

Under local anaesthesia the tissues covering the palatally impacted canine are removed with the help of a surgical guide to expose the tooth, to allow the bonding of an attachment on its surface for orthodontic traction.

Palatally impacted canine exposure using a surgical template

Under local anaesthesia the tissues covering the palatally impacted canine are removed to expose the tooth, to allow the bonding of an attachment on its surface for orthodontic traction. The surgeon relies on the surgical plan and their experience to localize the impacted canine.

Palatally impacted canine exposure using the conventional free-hand method

Eligibility Criteria

Age11 Years - 18 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • Patients between the age of 11-18 of the Department of Community Dentistry, Semmelweis University, who need surgical exposure and orthodontic eruption of their palatally impacted canines on one or both sides during their orthodontic treatment are included in this study.

You may not qualify if:

  • Uncontrolled systemic diseases that contraindicate orthodontic treatment or minor dental surgery,
  • Trauma in the patient's history in the vicinity of the surgical site.
  • Dental abnormalities (hyperdontia, hypodontia, etc.),
  • Congenital craniofacial disorders,
  • Permanent teeth extraction-based treatment,
  • Periodontal disease,
  • Cases in which the canine is to be brought into the position of the lateral incisor,
  • Agenesis of lateral incisors on the impaction side,
  • Documented learning disability,
  • Insufficient oral hygiene, and
  • Non-compliance during the combined orthodontic-surgical treatment.
  • Smoking

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Semmelweis University Department of Community Dentistry

Budapest, Budapest, 1088, Hungary

Location

Related Publications (1)

  • Kivovics M, Szanyi SM, Takacs A, Repasi M, Nemeth O, Mijiritsky E. Computer-assisted open exposure of palatally impacted canines for orthodontic eruption: A randomized clinical trial. J Dent. 2024 Aug;147:105110. doi: 10.1016/j.jdent.2024.105110. Epub 2024 Jun 20.

MeSH Terms

Conditions

Tooth, Impacted

Condition Hierarchy (Ancestors)

Tooth DiseasesStomatognathic Diseases

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
SINGLE
Who Masked
OUTCOMES ASSESSOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
senior lecturer

Study Record Dates

First Submitted

May 31, 2023

First Posted

June 18, 2023

Study Start

May 1, 2023

Primary Completion (Estimated)

April 30, 2028

Study Completion (Estimated)

June 30, 2028

Last Updated

April 22, 2026

Record last verified: 2026-04

Data Sharing

IPD Sharing
Will not share

Locations