NCT05907083

Brief Summary

Sexual dimorphism from skeletal remains a crucial step towards biological profile reconstruction since these are some of the last structures to remain after death. Paranasal sinuses remain intact even in extreme situations and are able to resist adverse environmental conditions due to their unique properties. The maxillary sinus is the largest of all paranasal sinuses and is considered as characteristic entity like human fingerprints for each person. Also, sphenoid air sinus is located deeply in the skull and is enveloped by different structures inside the sphenoid body. It is the least possibly affected by external deteriorating factors. Owing to limited research on the Egyptian population on the role of 3D volumetric assessment of paranasal sinuses in forensics, this study will be designed to investigate the significance of the volume of both sphenoid and maxillary sinuses in sexual discrimination.

Trial Health

35
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
204

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Aug 2023

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

June 8, 2023

Completed
10 days until next milestone

First Posted

Study publicly available on registry

June 18, 2023

Completed
1 month until next milestone

Study Start

First participant enrolled

August 1, 2023

Completed
1 year until next milestone

Primary Completion

Last participant's last visit for primary outcome

August 1, 2024

Completed
10 months until next milestone

Study Completion

Last participant's last visit for all outcomes

June 1, 2025

Completed
Last Updated

June 18, 2023

Status Verified

June 1, 2023

Enrollment Period

1 year

First QC Date

June 8, 2023

Last Update Submit

June 8, 2023

Conditions

Outcome Measures

Primary Outcomes (1)

  • Sexual dimorphism of maxillary air sinuses via volumetric segmentation

    1 year

Secondary Outcomes (2)

  • Sexual dimorphism of Sphenoid sinuses via volumetric segmentation

    1 year

  • Determination of age via sphenoid and maxillary air sinuses volumetric segmentation

    1 year

Study Arms (1)

Adult CBCT Scan

CBCT Radiation

Radiation: cone beam computer tomography

Interventions

Cone Beam CT Radiation

Also known as: CBCT
Adult CBCT Scan

Eligibility Criteria

Age20 Years - 60 Years
Sexall
Age GroupsAdult (18-64)
Sampling MethodProbability Sample
Study Population

CBCT maxillofacial scans belonging to Egyptian individuals will be examined

You may qualify if:

  • Adult Egyptian patients
  • Both sexes of age 20 to 60
  • Normal complete upper dental arch
  • Normal anatomy of the studied air sinuses.

You may not qualify if:

  • Scans with any facial pathosis like (tumors, odontogenic lesions, and bone lesions).
  • Scans showing any skeletal asymmetries, craniofacial traumas and developmental anomalies such as palatal cleft.
  • Patients with fractures or lesions affecting the studied sinuses.
  • Scans with insufficient Field of view
  • Scans of low-resolution quality.
  • Presence of considerable artifacts.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Design

Study Type
observational
Observational Model
CASE ONLY
Time Perspective
CROSS SECTIONAL
Sponsor Type
OTHER
Responsible Party
PRINCIPAL INVESTIGATOR
PI Title
PhD Candidate

Study Record Dates

First Submitted

June 8, 2023

First Posted

June 18, 2023

Study Start

August 1, 2023

Primary Completion

August 1, 2024

Study Completion

June 1, 2025

Last Updated

June 18, 2023

Record last verified: 2023-06