NCT05905575

Brief Summary

A family dyad-focused diabetes self-management for African American adults with type 2 diabetes is a randomized controlled trial (RCT) that aims to test the feasibility, acceptability, and efficacy of a family-dyad focused intervention on glycemic control (hemoglobin A1c) and health-related quality of life (HRQOL) in African American adults with type 2 diabetes (T2D).

Trial Health

75
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
208

participants targeted

Target at P75+ for phase_1 diabetes-mellitus-type-2

Timeline
9mo left

Started Jun 2023

Longer than P75 for phase_1 diabetes-mellitus-type-2

Geographic Reach
1 country

1 active site

Status
active not recruiting

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Progress80%
Jun 2023Jan 2027

First Submitted

Initial submission to the registry

April 18, 2023

Completed
1 month until next milestone

Study Start

First participant enrolled

June 1, 2023

Completed
14 days until next milestone

First Posted

Study publicly available on registry

June 15, 2023

Completed
3.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 31, 2027

Expected
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

January 31, 2027

Last Updated

March 5, 2026

Status Verified

March 1, 2026

Enrollment Period

3.7 years

First QC Date

April 18, 2023

Last Update Submit

March 3, 2026

Conditions

Outcome Measures

Primary Outcomes (4)

  • Change in diabetes control

    Change in glycosylated hemoglobin A1c will be measured with finger stick blood with a glycosylated hemoglobin A1CNow+ test. Changes in average percent of A1c will be used in the study.

    Baseline (T1) to immediate post-intervention at month 5 (T2)

  • Change in diabetes control

    Change in glycosylated hemoglobin A1c will be measured with finger stick blood with a glycosylated hemoglobin A1CNow+ test. Changes in average percent of A1c will be used in the study.

    Baseline (T1) to six months after intervention (T3) at month 11

  • Change in health-related quality of life

    Patient-Reported Outcomes Measurement Information System Global Health (PROMIS 10) will be used to measure changes in total scores of the global physical and global mental health. Scores range from 0-100 with higher scores indicating better quality of life.

    Baseline (T1) to immediate post-intervention at month 5 (T2)

  • Change in health-related quality of life

    Patient-Reported Outcomes Measurement Information System Global Health (PROMIS 10) will be used to measure changes in total scores of the global physical and global mental health. Scores range from 0-100 with higher scores indicating better quality of life.

    Baseline (T1) to six months after intervention (T3) at month 11

Secondary Outcomes (2)

  • Change in blood pressure control

    Baseline (T1) to immediate post-intervention at month 5 (T2)

  • Change in blood pressure control

    Baseline (T1) to six months after intervention (T3) at month 11

Study Arms (2)

Intervention

EXPERIMENTAL

Patient-family member dyads in the family dyad intervention arm will receive 1) 10 sessions (8 weekly and 2 biweekly) over 12 weeks of family-dyad-focused, virtual group sessions on diabetes self-management and family support; 2) family dyad-focused support component in each group session; and 3) individual family feedback telephone sessions.

Behavioral: Family dyad diabetes intervention

Control

NO INTERVENTION

All control participants will receive usual care from their primary healthcare provider. A condensed family dyad diabetes intervention will be delivered to the control participants by the end of the study.

Interventions

The goals of the intervention are to encourage participants to (1) daily self-manage diabetes and stress; (2) establish a healthy eating pattern; (3) engage in brisk walking of 150 or more minutes a week; and (4) use solution-focused problem-solving strategy and supportive family communication skills.

Intervention

Eligibility Criteria

Age18 Years - 90 Years
Sexall
Healthy VolunteersYes
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Individual with type 2 diabetes:
  • Self-identification as African American;
  • years or older
  • Type 2 diabetes diagnosis for at least six months;
  • A1c \> 7.0% at time of enrollment;
  • Being able to speak and read English;
  • Being able to walk;
  • Having an adult family member/close friend willing to co-participate in the study.
  • Family members:
  • Adults (18 years or older, with or without T2D);
  • Residing in the same household as the T2D participants;
  • Being a spouse, adult child or sibling; or close friend
  • Being able to walk;
  • Being able to speak and read English.

You may not qualify if:

  • Individual with T2D and family members:
  • Being pregnant or have an advanced or terminal condition;
  • Being cognitively impaired or unable to provide informed consent;
  • Lack conclusive evidence of T2D for patients with T2D.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

The Ohio State University College of Nursing

Columbus, Ohio, 43210, United States

Location

Related Publications (1)

  • Hu J, Mion LC, Tan A, Bartle-Haring S, Miller C, Joseph JJ. Family dyad-focused diabetes self-management intervention (FDSMI) for African American adults with type 2 diabetes: Study protocol. Contemp Clin Trials. 2025 Sep;156:108029. doi: 10.1016/j.cct.2025.108029. Epub 2025 Jul 22.

MeSH Terms

Conditions

Diabetes Mellitus, Type 2

Condition Hierarchy (Ancestors)

Diabetes MellitusGlucose Metabolism DisordersMetabolic DiseasesNutritional and Metabolic DiseasesEndocrine System Diseases

Study Design

Study Type
interventional
Phase
phase 1
Allocation
RANDOMIZED
Masking
NONE
Purpose
TREATMENT
Intervention Model
PARALLEL
Model Details: This two-arm randomized controlled trial (RCT) will test the feasibility, acceptability and efficacy of a family-dyad-focused intervention. A convenience sample will be recruited at clinics/pharmacy at Central Ohio. We will enroll a total of 208 participants in the study with104 African-Americans with T2D and one family member of each patient (104 patient-family member dyads). Patients with T2D will be randomized 1:1 to the intervention or control arm (n=52/arm). The family member of each patient will receive the same treatment as that assigned to the patient.
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

April 18, 2023

First Posted

June 15, 2023

Study Start

June 1, 2023

Primary Completion (Estimated)

January 31, 2027

Study Completion (Estimated)

January 31, 2027

Last Updated

March 5, 2026

Record last verified: 2026-03

Data Sharing

IPD Sharing
Will share

Data will be made available to the public as immediately and broadly as possible while safeguarding the privacy of participants and protecting confidential and proprietary data. All research data will be shared as requested in accordance with federal regulations, the Freedom of Information Act (FOIA). Requests from researchers will be reviewed by the project investigators, and we will provide the requesting researcher with the minimum necessary data; the shared data will not have any individual participant identifiers or specific clinic identifiers.

Shared Documents
STUDY PROTOCOL, SAP, ICF
Time Frame
Data will be made available to the public as immediately and broadly as possible while safeguarding the privacy of participants and protecting confidential and proprietary data.
Access Criteria
Requests will be reviewed by the project investigators (PI). In accordance with NIH policies and procedures regarding data use and data sharing, user registration will be required to access the les. Users must agree to the conditions of use governing access to the public release data, including restrictions against attempting to identify study participants, destruction of the data after analyses are completed, reporting responsibilities, restrictions on redistributions of the data to third parties, and proper acknowledgement of the data resource. Any presentations, abstracts, or publications must include an acknowledgement/reference of the research team. The requesting researcher(s) will be notified that they may only use the data for the purposes for which the data were requested and only by the individuals listed in the request. The requesting researcher(s) will be responsible for notifying the PI upon completion of analysis indicating the way the data were destroyed.

Locations