Trials Sponsors Conditions Drugs Pricing

Conditions

Medicine, Chinese Traditional Nasal Lavage Rhinitis, Allergic

Keywords

Rhinitis, AllergicNasal LavageMedicine, Chinese Traditional

Outcome Measures

Primary Outcomes (2)

Change of rhinitis symptom score
The effect of rhinorrhea, sneezing, nasal obstruction and itching on life quality was measuring by scores. Score 0 means no symptom, score 1 means symptomatic but not annoying, score 2 means troublesome symptoms and affecting part of daily activity or sleep and score 3 means annoying symptoms and affecting most daily activity or sleep.
Evaluated baseline and 2-month nasal lavage
Self-reported adverse events
Any adverse events occurring during the study period
Through study completion, an average of 2 months

Secondary Outcomes (5)

Change of swollen degree of inferior turbinates
Evaluated baseline and 2-month nasal lavage
Change of the second minimal cross-sectional area of the nasal cavity
Measured baseline and 2-month nasal lavage
Change of total inspiratory resistance
Measured baseline and 2-month nasal lavage
Change of score measured by Eustachian Tube Dysfunction Patient Questionnaire
Evaluated baseline and 2-month nasal lavage
Change of Eustachian Tube function test
Evaluated baseline and 2-month nasal lavage

Study Arms (2)

Chinese herbal medicine

EXPERIMENTAL

The bilateral nasal cavity was irrigated with a bottle of NeilMed containing 1 gram of Szechwan Lovage Rhizome, 1 gram of Biod Magnolia Bud, 0.5 gram of Taiwan Angelica Root, 0.5 gram of Wild Mint Herb, 1.5 gram of Baikal Skullcap Root, and 0.5 gram of Borneol dissolved in 240 ml of warm normal saline once a day.

Drug: Szechwan Lovage Rhizome, Biod Magnolia Bud, Taiwan Angelica Root, Wild Mint Herb, Baikal Skullcap Root, and Borneol

Placebo

PLACEBO COMPARATOR

The bilateral nasal cavity was irrigated with a bottle of NeilMed containing edible caramel dissolved in 240 ml of warm normal saline once a day.

Drug: edible caramel

Interventions

Szechwan Lovage Rhizome, Biod Magnolia Bud, Taiwan Angelica Root, Wild Mint Herb, Baikal Skullcap Root, and BorneolDrug

The bilateral nasal cavity was irrigated with a plastic bottle containing 1 gram of Szechwan Lovage Rhizome, 1 gram of Biod Magnolia Bud, 0.5 gram of Taiwan Angelica Root, 0.5 gram of Wild Mint Herb, 1.5 gram of Baikal Skullcap Root, and 0.5 gram of Borneol dissolved in 240 ml of warm normal saline once a day for 2 months.

Chinese herbal medicine

edible caramelDrug

The bilateral nasal cavity was irrigated with a plastic bottle containing edible caramel dissolved in 240 ml of warm normal saline once a day for 2 months.

Eligibility Criteria

Age20 Years+

Sexall

Healthy VolunteersNo

Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

Allergic rhinitis patients diagnosed based on the history and allergen test

You may not qualify if:

Sponsors & Collaborators

Taichung Veterans General Hospital
Otherlead

Study Sites (1)

Rong-San Jiang

Taichung, 40705, Taiwan

MeSH Terms

Conditions

Rhinitis, Allergic

Interventions

isoborneol

Condition Hierarchy (Ancestors)

RhinitisNose DiseasesRespiratory Tract DiseasesRespiratory HypersensitivityOtorhinolaryngologic DiseasesHypersensitivity, ImmediateHypersensitivityImmune System Diseases

Study Officials

Rong-San Jiang, MD, PhD
Taichung Veterans General Hospital
PRINCIPAL INVESTIGATOR

Enrollment

38 participants (actual enrollment reported by the registry).

Study Design

Study Type: interventional
Phase: phase 2
Allocation: RANDOMIZED
Masking: TRIPLE
Who Masked: PARTICIPANT, INVESTIGATOR, OUTCOMES ASSESSOR
Purpose: TREATMENT
Intervention Model: PARALLEL
Sponsor Type: OTHER
Responsible Party: SPONSOR

Study Record Dates

First Submitted

May 12, 2023

First Posted

June 13, 2023

Study Start

November 1, 2020

Actual (reported)

Nasal Irrigation With Chinese Herbal Medicine as an Adjunctive Treatment in Allergic Rhinitis

Brief Summary

Registry Overview

Trial Relationships

Study Timeline

Study Start

Primary Completion

Study Completion

First Submitted

First Posted

Conditions

Keywords

Outcome Measures

Primary Outcomes (2)

Secondary Outcomes (5)

Study Arms (2)

Chinese herbal medicine

Placebo

Interventions

Eligibility Criteria

You may qualify if:

You may not qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Interventions

Condition Hierarchy (Ancestors)

Study Officials

Enrollment

Study Design

Study Record Dates

Source record

Locations

Brief Summary

Registry Overview

Trial Relationships

Related Scientific Literature

Study Timeline

Study Start

Primary Completion

Study Completion

First Submitted

First Posted

Conditions

Keywords

Outcome Measures

Primary Outcomes (2)

Secondary Outcomes (5)

Study Arms (2)

Chinese herbal medicine

Placebo

Interventions

Eligibility Criteria

You may qualify if:

You may not qualify if:

Sponsors & Collaborators

Study Sites (1)

MeSH Terms

Conditions

Interventions

Condition Hierarchy (Ancestors)

Study Officials

Enrollment

Study Design

Study Record Dates

Source record

Locations