NCT05896345

Brief Summary

To conduct a RCT comparing SWL versus combined ODT and SWL as non-invasive methods for management of paediatrics radiolucent renal stone.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
76

participants targeted

Target at P50-P75 for not_applicable

Timeline
Completed

Started May 2018

Longer than P75 for not_applicable

Geographic Reach
1 country

1 active site

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

May 1, 2018

Completed
3.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

December 1, 2021

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

December 1, 2021

Completed
1.5 years until next milestone

First Submitted

Initial submission to the registry

May 31, 2023

Completed
9 days until next milestone

First Posted

Study publicly available on registry

June 9, 2023

Completed
Last Updated

June 9, 2023

Status Verified

May 1, 2023

Enrollment Period

3.6 years

First QC Date

May 31, 2023

Last Update Submit

May 31, 2023

Conditions

Outcome Measures

Primary Outcomes (1)

  • Assess the stone free rate measured by computed tomograghy as asymptomatic insignificant residual fragments less than 3 mm

    percentage of patient who are stone free

    3 month

Study Arms (2)

SWL

ACTIVE COMPARATOR

Shockwave Lithotripsy (SWL)

Device: SWL

SWL and ODT

ACTIVE COMPARATOR

Shockwave Lithotripsy (SWL) and Oral Dissolution Therapy (ODT)

Combination Product: SWL and ODT

Interventions

SWLDEVICE

Shockwave Lithotripsy (SWL) For Paediatrics Radiolucent Renal Stone

SWL
SWL and ODTCOMBINATION_PRODUCT

Shockwave Lithotripsy (SWL) and Oral Dissolution Therapy (ODT) For Paediatrics Radiolucent Renal Stone

SWL and ODT

Eligibility Criteria

AgeUp to 18 Years
Sexall
Healthy VolunteersNo
Age GroupsChild (0-17), Adult (18-64)

You may qualify if:

  • cm renal stone
  • Normal Serum creatinine
  • Radiolucent stone with Hounsfield units less than 400

You may not qualify if:

  • Bleeding diatheses.
  • Patients with a pacemaker.
  • uncontrolled UTIs.
  • Severe skeletal malformations.
  • Arterial aneurysm in the vicinity of the stone.
  • Anatomical obstruction distal to the stone.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Urology and Nephrology Center

Al Mansurah, Outside U.S./Canada, 35516, Egypt

Location

Study Design

Study Type
interventional
Phase
not applicable
Allocation
RANDOMIZED
Masking
DOUBLE
Who Masked
PARTICIPANT, INVESTIGATOR
Purpose
TREATMENT
Intervention Model
PARALLEL
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 31, 2023

First Posted

June 9, 2023

Study Start

May 1, 2018

Primary Completion

December 1, 2021

Study Completion

December 1, 2021

Last Updated

June 9, 2023

Record last verified: 2023-05

Data Sharing

IPD Sharing
Will not share

Locations