Jejunostomy-Based Early Enteral Feeding After Esophagectomy
The Study Wonders Whether Early Gastric Force Feeding Can Reduce the Infection Rate and Whether the External Reaction Can Simultaneously Promote the Gastric Motility of the Gastrointestinal Tract Peristalsis Can Reduce the Complications of Postoperative Neck and Wound Anastomosis Leakage, Provide Postoperative Care for Intact Esophagus, and Reduce Postoperative Mortality.
1 other identifier
interventional
70
1 country
1
Brief Summary
Esophagectomy with reconstruction for esophageal cancer is associated with delayed gastrointestinal recovery and substantial postoperative morbidity. Whether early jejunostomy-based enteral feeding can be safely initiated after esophagectomy remains uncertain.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P50-P75 for not_applicable
Started Nov 2022
Typical duration for not_applicable
1 active site
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
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Study Timeline
Key milestones and dates
First Submitted
Initial submission to the registry
September 6, 2022
CompletedStudy Start
First participant enrolled
November 1, 2022
CompletedFirst Posted
Study publicly available on registry
June 7, 2023
CompletedPrimary Completion
Last participant's last visit for primary outcome
July 8, 2025
CompletedStudy Completion
Last participant's last visit for all outcomes
July 8, 2025
CompletedJune 17, 2026
July 1, 2025
2.7 years
September 6, 2022
June 15, 2026
Conditions
Outcome Measures
Primary Outcomes (1)
gastrointestinal emptying time
Start timing the first bowel movement or exhaust time after surgery
up to 72 hours (time of the first bowel movement or exhaust after surgery )
Secondary Outcomes (4)
Infection and Inflammation
up to 72 hours
Postoperative complications
up to72 hours (time of the first bowel movement or exhaust after surgery )
Nutritional risk
up to 72 hours
Postoperative recovery
up to 60 days
Study Arms (2)
Early intestinal force-feeding and drugs to promote gastrointestinal motility
EXPERIMENTALgiving force-feeding after gas or defecation
NO INTERVENTIONInterventions
Enteral force feeding with 5% dextrose injection within 24 hours after operation
Eligibility Criteria
You may qualify if:
- Esophagectomy
- Esophagectomy ＆ reconstruction
- Esophagotomy
- Esophageal reconstruction-with gastric tube
- Esophageal reconstruction-with colon
- Esophageal reconstruction with small intestine
You may not qualify if:
- Gastrointestinal perforation
- Postoperative hemorrhage
- Intestinal obstruction
- Shock
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (1)
National Taiwan University Hospital
Taipei, Taiwan, 100, Taiwan
Study Design
- Study Type
- interventional
- Phase
- not applicable
- Allocation
- RANDOMIZED
- Masking
- NONE
- Purpose
- TREATMENT
- Intervention Model
- PARALLEL
- Sponsor Type
- OTHER
- Responsible Party
- SPONSOR
Study Record Dates
First Submitted
September 6, 2022
First Posted
June 7, 2023
Study Start
November 1, 2022
Primary Completion
July 8, 2025
Study Completion
July 8, 2025
Last Updated
June 17, 2026
Record last verified: 2025-07
Data Sharing
- IPD Sharing
- Will not share