NCT05891106

Brief Summary

This study will be used to support assessment of AIR OPTIX® NIGHT \& DAY® AQUA (AONDA) Soft Contact Lenses' safety and performance in accordance with updated European Union Medical Device Regulation (EU MDR) requirements.

Trial Health

87
On Track

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Enrollment
55

participants targeted

Target at P25-P50 for all trials

Timeline
Completed

Started Jun 2023

Geographic Reach
1 country

3 active sites

Status
completed

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

First Submitted

Initial submission to the registry

May 24, 2023

Completed
13 days until next milestone

First Posted

Study publicly available on registry

June 6, 2023

Completed
22 days until next milestone

Study Start

First participant enrolled

June 28, 2023

Completed
12 days until next milestone

Primary Completion

Last participant's last visit for primary outcome

July 10, 2023

Completed
Same day until next milestone

Study Completion

Last participant's last visit for all outcomes

July 10, 2023

Completed
Last Updated

July 20, 2023

Status Verified

July 1, 2023

Enrollment Period

12 days

First QC Date

May 24, 2023

Last Update Submit

July 18, 2023

Conditions

Outcome Measures

Primary Outcomes (1)

  • Change from baseline in corneal pain at the Follow-up Visit

    The Investigator will review the subject's chart and document change from baseline in corneal pain at the Follow-up visit as "improved, similar, or worsened." The Baseline Visit is defined as the first visit where the AONDA therapeutic contact lens was placed on eye as part of a treatment plan for an ocular condition. The Follow-up Visit is defined as the first visit where the AONDA therapeutic contact lens was removed from the eye, or the first visit following the removal of the contact lens if, for example, the contact lens was removed between visits.

    Baseline, Follow-Up Visit (up to 1 year following the Baseline Visit)

Study Arms (1)

AONDA Therapeutic

Lotrafilcon A contact lenses worn therapeutically as a bandage lens as instructed by the eye care professional

Device: Lotrafilcon A contact lenses

Interventions

CE-marked silicone hydrogel contact lenses

Also known as: AONDA, AIR OPTIX® NIGHT & DAY® AQUA
AONDA Therapeutic

Eligibility Criteria

Age18 Years+
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

Investigators will enroll charts following a pre-identified process.

You may qualify if:

  • Diagnosis of a corneal condition with pain for which AONDA Soft Contact Lens as a therapeutic contact lens was placed on one or both eye(s) at Baseline.
  • Baseline and Follow-up (up to 1 year from Baseline) charts available.

You may not qualify if:

  • Had a condition (pathological, behavioral, and/or situational) that contraindicated therapeutic contact lens wear or confounds study results during the data collection period, as determined or known by the Investigator.
  • Used systemic or ocular medication that would confound study results during the data collection period, as determined or known by the Investigator.

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (3)

Vision Health Institute

Orlando, Florida, 32803, United States

Location

Franklin Park Eye Center PC

Franklin Park, Illinois, 60131, United States

Location

Optometry Group, PLLC

Memphis, Tennessee, 38111, United States

Location

MeSH Terms

Conditions

EntropionCorneal EdemaCorneal Dystrophies, HereditaryCorneal UlcerBell PalsyKeratoconjunctivitisSjogren's Syndrome

Condition Hierarchy (Ancestors)

Eyelid DiseasesEye DiseasesCorneal DiseasesEye Diseases, HereditaryGenetic Diseases, InbornCongenital, Hereditary, and Neonatal Diseases and AbnormalitiesEye InfectionsInfectionsKeratitisHerpesviridae InfectionsDNA Virus InfectionsVirus DiseasesMouth DiseasesStomatognathic DiseasesFacial Nerve DiseasesCranial Nerve DiseasesNervous System DiseasesConjunctivitisConjunctival DiseasesArthritis, RheumatoidArthritisJoint DiseasesMusculoskeletal DiseasesRheumatic DiseasesXerostomiaSalivary Gland DiseasesDry Eye SyndromesLacrimal Apparatus DiseasesConnective Tissue DiseasesSkin and Connective Tissue DiseasesAutoimmune DiseasesImmune System Diseases

Study Officials

  • Clinical Trial Lead, CRD Vision Care

    Alcon Research, LLC

    STUDY DIRECTOR

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
RETROSPECTIVE
Sponsor Type
INDUSTRY
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 24, 2023

First Posted

June 6, 2023

Study Start

June 28, 2023

Primary Completion

July 10, 2023

Study Completion

July 10, 2023

Last Updated

July 20, 2023

Record last verified: 2023-07

Data Sharing

IPD Sharing
Will not share

Locations