NCT05888025

Brief Summary

This is a two phase study. In phase 1, a focus group (N=5) will be conducted to adapt MBCT-T for use in the study population. In phase 2, a single-arm trial will be conducted examining four, weekly sessions of preoperative MBCT-T in subjects with high pain catastrophizing scheduled for spine surgery (N=20). Subjects will then be followed for two weeks postoperatively.

Trial Health

53
Monitor

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial recruitment is currently suspended
Enrollment
25

participants targeted

Target at below P25 for not_applicable pain

Timeline
16mo left

Started Jan 2020

Longer than P75 for not_applicable pain

Geographic Reach
1 country

2 active sites

Status
suspended

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

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Study Timeline

Key milestones and dates

Study Progress83%
Jan 2020Oct 2027

Study Start

First participant enrolled

January 9, 2020

Completed
3.4 years until next milestone

First Submitted

Initial submission to the registry

May 25, 2023

Completed
11 days until next milestone

First Posted

Study publicly available on registry

June 5, 2023

Completed
4 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

June 1, 2027

Expected
4 months until next milestone

Study Completion

Last participant's last visit for all outcomes

October 1, 2027

Last Updated

January 6, 2026

Status Verified

January 1, 2026

Enrollment Period

7.4 years

First QC Date

May 25, 2023

Last Update Submit

January 2, 2026

Conditions

Outcome Measures

Primary Outcomes (2)

  • Percentage of Participants who Attend More than Half of Scheduled Sessions

    Up to Week 8 (End of Intervention)

  • Client Satisfaction Questionnaire (CSQ-8) Score

    The CSQ-8 is an 8-item questionnaire assessing satisfaction with the intervention. Each item is rated on a 4-point scale from 1-4. The total score is the sum of responses and ranges from 8 to 32, with the higher number indicating greater satisfaction.

    Week 8 (End of Intervention)

Secondary Outcomes (1)

  • Change in Pain Catastrophizing Scale (PCS) Score

    Baseline, Week 8

Study Arms (1)

MBCT-T

EXPERIMENTAL

Participants with high pain catastrophizing who are scheduled for spine surgery will receive four weekly sessions of preoperative telephone-delivered mindfulness-based cognitive therapy (MBCT-T). They will then be followed for two weeks postoperatively.

Behavioral: Telephone-Delivered Mindfulness-based Cognitive Therapy (MBCT-T)

Interventions

MBCT-T will be delivered in groups of four to eight subjects by telephone using a conference line with NYULH WebEx. Participants will receive a workbook containing session content and home practice logs and audio guides for home practice. Subjects will complete individual orientation sessions with the MBCT-T facilitator prior to start of the group sessions. The four subsequent weekly group sessions are approximately 90 minutes long. Participants will be encouraged to practice daily meditation in between group sessions for 20-30 minutes, six days per week

MBCT-T

Eligibility Criteria

Age18 Years - 75 Years
Sexall
Healthy VolunteersNo
Age GroupsAdult (18-64), Older Adult (65+)

You may qualify if:

  • Scheduled for one or two level lumbar spine surgery requiring an inpatient stay as well as patients having ambulatory 1 or 2 level lumbar spine surgeries
  • PCS score ≥ 20
  • Able to provide voluntary informed consent
  • Telephone access
  • Internet access

You may not qualify if:

  • Non-English speaking
  • Cognitively impaired, by history
  • Bipolar disorder
  • Borderline personality disorder
  • Active post-traumatic stress disorder
  • Schizoaffective disorder or any other disorder characterized by delusions or hallucinations
  • History of self-harm or suicidality in past three months

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (2)

NYU Langone Health

Brooklyn, New York, 11220, United States

Location

NYU Langone Health

New York, New York, 10016, United States

Location

MeSH Terms

Conditions

Pain

Condition Hierarchy (Ancestors)

Neurologic ManifestationsSigns and SymptomsPathological Conditions, Signs and Symptoms

Study Officials

  • Lisa Doan, MD

    NYU Langone Health

    PRINCIPAL INVESTIGATOR

Study Design

Study Type
interventional
Phase
not applicable
Allocation
NA
Masking
NONE
Purpose
TREATMENT
Intervention Model
SINGLE GROUP
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 25, 2023

First Posted

June 5, 2023

Study Start

January 9, 2020

Primary Completion (Estimated)

June 1, 2027

Study Completion (Estimated)

October 1, 2027

Last Updated

January 6, 2026

Record last verified: 2026-01

Data Sharing

IPD Sharing
Will share

The de-identified participant data from the final research dataset used in the published manuscript will be shared upon reasonable request beginning 9 months and ending 36 months following article publication or as required by a condition of awards and agreements supporting the research provided the investigator who proposes to use the data executes a data use agreement with NYU Langone Health. Requests may be directed to: lisa.doan@nyulangone.org. The protocol and statistical analysis plan will be made available on Clinicaltrials.gov only as required by federal regulation or as a condition of awards and agreements supporting the research.

Shared Documents
STUDY PROTOCOL, SAP
Time Frame
Beginning 9 months and ending 36 months following article publication or as required by a condition of awards and agreements supporting the research.
Access Criteria
The investigator who proposed to use the data will be granted access upon reasonable request. Requests should be directed to lisa.doan@nyulangone.org. To gain access, data requestors will need to sign a data access agreement.

Locations