TRIAD Appendicitis Decision-making Surveys
TRIAD
Treatment Individualized Appendicitis Decision-Making (TRIAD) Patient Surveys
2 other identifiers
observational
3,000
1 country
17
Brief Summary
While appendectomy has been the main treatment of appendicitis for over 100 years, recent European studies found that, at least among highly selected patients, antibiotics alone can be an effective alternative. Surgeons and patients alike have a difficult time deciding if surgery or antibiotics are the best choice to treat appendicitis. The goal of the TRIAD is to evaluate the patients who are a part of the TRIAD implementation program and assess satisfaction and decisional regret for patients with appendicitis. This information will be used to inform the design of decision-support interventions to help patients improve their ability to make an informed decision in-line with their preferences and values.
Trial Health
Trial Health Score
Automated assessment based on enrollment pace, timeline, and geographic reach
participants targeted
Target at P75+ for all trials
Started Oct 2022
Typical duration for all trials
17 active sites
Health score is calculated from publicly available data and should be used for screening purposes only.
Trial Relationships
Click on a node to explore related trials.
Study Timeline
Key milestones and dates
Study Start
First participant enrolled
October 1, 2022
CompletedFirst Submitted
Initial submission to the registry
May 24, 2023
CompletedFirst Posted
Study publicly available on registry
June 2, 2023
CompletedPrimary Completion
Last participant's last visit for primary outcome
October 1, 2024
CompletedStudy Completion
Last participant's last visit for all outcomes
October 1, 2025
CompletedJune 18, 2023
June 1, 2023
2 years
May 24, 2023
June 13, 2023
Conditions
Keywords
Outcome Measures
Primary Outcomes (1)
Ottawa Decisional Conflict Scale
Ottawa Decisional Conflict Scale (DCS) measures personal perceptions of uncertainty in choosing options; modifiable factors contributing to uncertainty; and effective decision making
3 years
Study Arms (2)
Surgery
Patients who chose to receive surgery as treatment for their appendicitis.
Antibiotics
Patients who chose to receive antibiotics as treatment for their appendicitis.
Interventions
Measure Ottawa Decisional Regret at baseline when patients receive a diagnosis of appendicitis.
Eligibility Criteria
Any patient 18+ years old or older who has been diagnosed with appendicitis at a participating TRIAD clinical site after anticipated exclusion due to age, medical condition, or radiographic finding.
You may qualify if:
- Any patient the clinical team feels is appropriate for considering either surgery or antibiotics for their initial appendicitis treatment
You may not qualify if:
- Pregnant patients
- Immunocompromised patients
- Patients with high complication risk of recurrent infections
- Evidence of severe phlegmon or walled off abscess or free air on imaging
- Septic shock
- Diffuse peritonitis
- Patients under 18 years old
Contact the study team to confirm eligibility.
Sponsors & Collaborators
Study Sites (17)
Kaiser Permanente Baldwin Park
Baldwin Park, California, 90027, United States
Kaiser Permanente Los Angeles
Los Angeles, California, 90027, United States
Kaiser Permanente Riverside
Riverside, California, 92555, United States
Grady Health System / Morehouse School of Medicine
Atlanta, Georgia, 30305, United States
Northwestern Medicine
Chicago, Illinois, 60611, United States
University of Iowa Hospitals and Clinics
Iowa City, Iowa, 52242, United States
Boston Medical Center
Boston, Massachusetts, 02118, United States
Michigan Medicine- University of Michigan
Ann Arbor, Michigan, 48109, United States
Columbia University Medical Center
New York, New York, 10032, United States
Atrium Health
Charlotte, North Carolina, 28204, United States
Medical University of South Carolina
Charleston, South Carolina, 29425, United States
Lyndon B Johnson- Harris Health
Houston, Texas, 77026, United States
The University of Texas Health Science Center at Houston
Houston, Texas, 77026, United States
Texas Tech University
Lubbock, Texas, 79430, United States
Harborview Medical Center
Seattle, Washington, 98104, United States
Northwest Hospital and Medical Center
Seattle, Washington, 98133, United States
University of Washington Medical Center
Seattle, Washington, 98195, United States
Related Publications (1)
CODA Collaborative; Flum DR, Davidson GH, Monsell SE, Shapiro NI, Odom SR, Sanchez SE, Drake FT, Fischkoff K, Johnson J, Patton JH, Evans H, Cuschieri J, Sabbatini AK, Faine BA, Skeete DA, Liang MK, Sohn V, McGrane K, Kutcher ME, Chung B, Carter DW, Ayoung-Chee P, Chiang W, Rushing A, Steinberg S, Foster CS, Schaetzel SM, Price TP, Mandell KA, Ferrigno L, Salzberg M, DeUgarte DA, Kaji AH, Moran GJ, Saltzman D, Alam HB, Park PK, Kao LS, Thompson CM, Self WH, Yu JT, Wiebusch A, Winchell RJ, Clark S, Krishnadasan A, Fannon E, Lavallee DC, Comstock BA, Bizzell B, Heagerty PJ, Kessler LG, Talan DA. A Randomized Trial Comparing Antibiotics with Appendectomy for Appendicitis. N Engl J Med. 2020 Nov 12;383(20):1907-1919. doi: 10.1056/NEJMoa2014320. Epub 2020 Oct 5.
PMID: 33017106RESULT
Related Links
MeSH Terms
Conditions
Interventions
Condition Hierarchy (Ancestors)
Study Officials
- PRINCIPAL INVESTIGATOR
Giana Davidson, MD, MPH
University of Washington
Central Study Contacts
Study Design
- Study Type
- observational
- Observational Model
- CASE ONLY
- Time Perspective
- PROSPECTIVE
- Sponsor Type
- OTHER
- Responsible Party
- PRINCIPAL INVESTIGATOR
- PI Title
- Associate Professor: School of Medicine
Study Record Dates
First Submitted
May 24, 2023
First Posted
June 2, 2023
Study Start
October 1, 2022
Primary Completion
October 1, 2024
Study Completion
October 1, 2025
Last Updated
June 18, 2023
Record last verified: 2023-06