Somatic Symptoms in Autism Spectrum Disorder: Data Integration

NCT05886361 | Completed

• 1 other identifier: 202206027RINA
• Study Type: observational
• Target: 1,423
• Locations: 0 countries
• Sites: N/A

Brief Summary

Autistic patients have higher chances commorbid somatic symptoms. Therefore, it leads to more health-related concerns, such as autoimmune disease, gastrointestinal disease, cardiovascular disease, autonomic disorders. On average, autistic patient's life span is 16 years shorter than non-autistic patients. Furthermore, autistic patients are not able to convey or communicate their somatic symptoms in a clear and comprehensive manner. This leads to unable to receive proper health care in a timely manner.

Conditions

Autism Spectrum Disorder; Somatic Symptom Disorder

Outcome Measures

Primary Outcomes (4)

• Patient health questionnaire-15, PHQ-15

  range from 0 to 2 for each item, total score range from 0 to 30. Higher the score, worse the level of somatization

  8 years

• Health assessment questionnairse, HAQ

  range from 0 to 3 for each item. Higher the score, worse the disability

  8 years

• Beck depression inventory, BDI

  range from 0 to 3 for each item. Higher the score, worse the depression

  8 years

• Beck anxiety inventory

  range from 0 to 3 for each item. Total score 0 to 63. Higher the score, worse the anxiety

  8 years

Study Arms (3)

ASD

Diagnosed with DSM-5 autism spectrum disorder

Other: No intervention involved

Clinical

Patients with anxiety, depression, somatic symptoms which are non-psychotic and non-organic

Other: No intervention involved

Control

Healthy control without psychiatric disorder or chronic somatic symptoms

Other: No intervention involved

Interventions

No intervention involved OTHER

No intervention involved

ASD; Clinical; Control

Eligibility Criteria

• Age: 15 Years - 70 Years
• Sex: all
• Healthy Volunteers: No
• Age Groups: Child (0-17), Adult (18-64), Older Adult (65+)
• Sampling Method: Non-Probability Sample

Study Population

as mentioned earlier, it is a retrospective study with existed data. Therefore, the 1423 participants are already collected in the past. We separate these existed data into three groups as mentioned in the eligibility criteria

You may qualify if:

• ASD group: diagnosed with DSM-5 autism spectrum disorder
• clinical group: anxiety, depression, somatic disorder who are non-psychotic and non-organic
• control group: healthy control without psychiatric disorder or chronic somatic symptoms
• age between 15 and 70

You may not qualify if:

• psychiatric disorders such as schezophrenia, mood disorder.
• major physical disorder which can be potentially lethal
• who cannot read or comprehend the survey and questionnaire

Sponsors & Collaborators

• National Taiwan University Hospital: lead

MeSH Terms

Conditions

Autism Spectrum Disorder

Condition Hierarchy (Ancestors)

Child Development Disorders, Pervasive; Neurodevelopmental Disorders; Mental Disorders

Study Design

• Study Type: observational
• Observational Model: CASE CONTROL
• Time Perspective: RETROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: SPONSOR

Study Record Dates

• First Submitted: May 4, 2023
• First Posted: June 2, 2023
• Study Start: January 1, 2014
• Primary Completion: May 31, 2022
• Study Completion: May 31, 2022
• Last Updated: June 2, 2023

Record last verified: 2022-06