NCT05885711

Brief Summary

The goal of this multicenter observational study is to study self-management of pessary therapy in patients with pelvic organ prolapse. The primary question it aims to answer is:

  • how many patients succeed learning self-management if offered a standardized training? Secondary outcomes are:
  • how many patients are willing to learn self-management?
  • what patient factors contribute to successfully learning self-management and willingness to self-manage?
  • how satisfied are patients with pessary therapy and self-management?
  • the occurrence of side-effects
  • continuation and quitting of pessary therapy and self-management
  • cross-over to surgery
  • number of visits to doctor because of pessary therapy
  • healthcare costs Participants will be asked to fill in questionnaires three times during the study (upon inclusion, 6 weeks and 12 months after starting self-management or after starting pessary therapy with a correctly fitting pessary). Researchers will compare the self-managing patient to the non-self-managing patients.

Trial Health

43
At Risk

Trial Health Score

Automated assessment based on enrollment pace, timeline, and geographic reach

Trial has exceeded expected completion date
Enrollment
288

participants targeted

Target at P75+ for all trials

Timeline
Completed

Started Jan 2023

Typical duration for all trials

Geographic Reach
1 country

1 active site

Status
unknown

Health score is calculated from publicly available data and should be used for screening purposes only.

Trial Relationships

Click on a node to explore related trials.

Study Timeline

Key milestones and dates

Study Start

First participant enrolled

January 9, 2023

Completed
4 months until next milestone

First Submitted

Initial submission to the registry

May 11, 2023

Completed
22 days until next milestone

First Posted

Study publicly available on registry

June 2, 2023

Completed
1.6 years until next milestone

Primary Completion

Last participant's last visit for primary outcome

January 1, 2025

Completed
2 months until next milestone

Study Completion

Last participant's last visit for all outcomes

March 1, 2025

Completed
Last Updated

June 2, 2023

Status Verified

May 1, 2023

Enrollment Period

2 years

First QC Date

May 11, 2023

Last Update Submit

June 1, 2023

Conditions

Keywords

pelvic organ prolapsepessaryself-management

Outcome Measures

Primary Outcomes (1)

  • Number of patients that succeed in learning self-management of the pessary

    Patients were offered self-management training, after explanation they were asked to remove and insert their pessary twice. Succes was defined as removing and inserting the pessary completely independent the second time.

    immediately after self-management training, it is determined whether patients can remove and insert their pessary

Interventions

self-managing a pessary: removing, cleaning and inserting

Eligibility Criteria

Age18 Years+
Sexfemale
Age GroupsAdult (18-64), Older Adult (65+)
Sampling MethodNon-Probability Sample
Study Population

New patients that get fitted a pessary in second line (hospital)

You may qualify if:

  • fitted a ring, sieve of knob pessary
  • above 18 years old
  • able to understand patient information

You may not qualify if:

  • fitted a new pessary to replace an old one (continuing former pessary therapy)
  • fitted a new pessary after they experienced adverse effects of a former pessary

Contact the study team to confirm eligibility.

Sponsors & Collaborators

Study Sites (1)

Zuyderland Medisch Centrum

Heerlen, Netherlands

RECRUITING

MeSH Terms

Conditions

Pelvic Organ Prolapse

Interventions

Self-Management

Condition Hierarchy (Ancestors)

ProlapsePathological Conditions, AnatomicalPathological Conditions, Signs and Symptoms

Intervention Hierarchy (Ancestors)

RehabilitationHealth ServicesHealth Care Facilities Workforce and Services

Study Officials

  • M Weemhoff

    Zuyderland Medisch Centrum

    PRINCIPAL INVESTIGATOR

Central Study Contacts

M Weemhoff, MD, PhD

CONTACT

Research Nurses

CONTACT

Study Design

Study Type
observational
Observational Model
COHORT
Time Perspective
PROSPECTIVE
Target Duration
12 Months
Sponsor Type
OTHER
Responsible Party
SPONSOR

Study Record Dates

First Submitted

May 11, 2023

First Posted

June 2, 2023

Study Start

January 9, 2023

Primary Completion

January 1, 2025

Study Completion

March 1, 2025

Last Updated

June 2, 2023

Record last verified: 2023-05

Locations