Peroneal Nerve Dysfunction in Epiphyseal Transfer

NCT05884827 | Recruiting

• 1 other identifier: EMG in Epiphyseal transfer
• Study Type: observational
• Target: 15
• Locations: 1 country
• Sites: 1

Brief Summary

Assessment of peroneal nerve dysfunction after proximal fibular epiphyseal resection and evaluation of clinical outcome and EMG changes.

Conditions

Epiphyseal Arrest

Outcome Measures

Primary Outcomes (1)

• Assessment of Tibialis anterior dysfunction after proximal fibular epiphyseal harvesting

  Electromyography changes at 3 weeks , 6 weeks , 3 months and 6 months to assess the affection of tibialis anterior muscle \& peroneal nerve

  Six months

Interventions

EMG DEVICE

Measure the electrical activity of the muscle and nerve

Eligibility Criteria

• Age: 18 Months - 14 Years
• Sex: all
• Age Groups: Child (0-17)
• Sampling Method: Non-Probability Sample

Study Population

Children with destroyed epiphysis whatever the cause of destruction and with preserved proximal fibular epiphysis

You may qualify if:

• all patients candidate for epiphyseal transfer are included ( patients with traumatic bone defect, congenital malformations, malignant bone lesions and infection )

You may not qualify if:

• patients in which there's no injury of nerve supply of tibialis anterior has occurred intraoperative

Sponsors & Collaborators

• Assiut University: lead

Study Sites (1)

Omar

Asyut, 71511, Egypt

RECRUITING

Related Publications (6)

• Zelenski N, Brigman BE, Levin LS, Erdmann D, Eward WC. The vascularized fibular graft in the pediatric upper extremity: a durable, biological solution to large oncologic defects. Sarcoma. 2013;2013:321201. doi: 10.1155/2013/321201. Epub 2013 Oct 7.

  PMID: 24222724 BACKGROUND

• Shammas RL, Avashia YJ, Farjat AE, Catanzano AA, Levin LS, Eward WC, Brigman BE, Erdmann D. Vascularized Fibula-Based Physis Transfer: A Follow-Up Study of Longitudinal Bone Growth and Complications. Plast Reconstr Surg Glob Open. 2017 May 25;5(5):e1352. doi: 10.1097/GOX.0000000000001352. eCollection 2017 May.

  PMID: 28607872 BACKGROUND

• Ghert M, Colterjohn N, Manfrini M. The use of free vascularized fibular grafts in skeletal reconstruction for bone tumors in children. J Am Acad Orthop Surg. 2007 Oct;15(10):577-87. doi: 10.5435/00124635-200710000-00001.

  PMID: 17916780 BACKGROUND

• Innocenti M, Delcroix L, Romano GF. Epiphyseal transplant: harvesting technique of the proximal fibula based on the anterior tibial artery. Microsurgery. 2005;25(4):284-92. doi: 10.1002/micr.20130.

  PMID: 15934045 BACKGROUND

• Sales de Gauzy J, Accadbled F, Gomez Brouchet A, Abid A. Case report: histologic study of a human epiphyseal transplant at 3 years after implantation. Clin Orthop Relat Res. 2009 Jul;467(7):1915-20. doi: 10.1007/s11999-009-0723-z. Epub 2009 Feb 11.

  PMID: 19212796 BACKGROUND

• Grimer RJ. Surgical options for children with osteosarcoma. Lancet Oncol. 2005 Feb;6(2):85-92. doi: 10.1016/S1470-2045(05)01734-1.

  PMID: 15683817 BACKGROUND

Central Study Contacts

Ahmed Moustafa Elsese, Resident

CONTACT

01009246781; Ahmedelsese@med.aun.edu.eg

Omar Ahmed Refai, Consultant

CONTACT

01003412298; Omarrefai@med.aun.edu.eg

Study Design

• Study Type: observational
• Observational Model: CASE ONLY
• Time Perspective: PROSPECTIVE
• Sponsor Type: OTHER
• Responsible Party: PRINCIPAL INVESTIGATOR
• PI Title: Principal investigator

Study Record Dates

• First Submitted: April 23, 2023
• First Posted: June 1, 2023
• Study Start: June 1, 2023
• Primary Completion: August 1, 2024
• Study Completion: September 1, 2024
• Last Updated: February 6, 2024

Record last verified: 2024-02

Locations

EG (1)